BRD-K47717570_NBQX disodium salt_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

114 genes differentially expressed following the BRD-K47717570_NBQX disodium salt_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP3 aquaporin 3 (Gill blood group)
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CALML3 calmodulin-like 3
CD40 CD40 molecule, TNF receptor superfamily member 5
CD9 CD9 molecule
CHGB chromogranin B
COG7 component of oligomeric golgi complex 7
CRABP2 cellular retinoic acid binding protein 2
CTNND1 catenin (cadherin-associated protein), delta 1
CX3CL1 chemokine (C-X3-C motif) ligand 1
DENND1B DENN/MADD domain containing 1B
EHD3 EH-domain containing 3
EZR ezrin
FABP4 fatty acid binding protein 4, adipocyte
FBLN1 fibulin 1
FCGBP Fc fragment of IgG binding protein
FGFR2 fibroblast growth factor receptor 2
FRZB frizzled-related protein
FZD1 frizzled class receptor 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GNAS GNAS complex locus
GP2 glycoprotein 2 (zymogen granule membrane)
HIST1H1C histone cluster 1, H1c
HIST1H2AE histone cluster 1, H2ae
HIST1H2BD histone cluster 1, H2bd
HIST1H3H histone cluster 1, H3h
HIST2H2BE histone cluster 2, H2be
HK2 hexokinase 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HSPA4 heat shock 70kDa protein 4
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IGHM immunoglobulin heavy constant mu
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
JCHAIN joining chain of multimeric IgA and IgM
KRT13 keratin 13, type I
KRT15 keratin 15, type I
KRT19 keratin 19, type I
MME membrane metallo-endopeptidase
MMP12 matrix metallopeptidase 12
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
OLFM4 olfactomedin 4
OSBPL10 oxysterol binding protein-like 10
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PERP PERP, TP53 apoptosis effector
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PON3 paraoxonase 3
PPAP2B phosphatidic acid phosphatase type 2B
PTPRK protein tyrosine phosphatase, receptor type, K
RAB21 RAB21, member RAS oncogene family
RAI14 retinoic acid induced 14
RGCC regulator of cell cycle
SCGB1D2 secretoglobin, family 1D, member 2
SELENBP1 selenium binding protein 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SRGN serglycin
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STC1 stanniocalcin 1
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TACSTD2 tumor-associated calcium signal transducer 2
TBXA2R thromboxane A2 receptor
TCTA T-cell leukemia translocation altered
TMEM158 transmembrane protein 158 (gene/pseudogene)
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD2 abhydrolase domain containing 2
AGR2 anterior gradient 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AREG amphiregulin
AXL AXL receptor tyrosine kinase
BMI1 BMI1 proto-oncogene, polycomb ring finger
BST2 bone marrow stromal cell antigen 2
COL5A1 collagen, type V, alpha 1
DICER1 dicer 1, ribonuclease type III
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
GPX3 glutathione peroxidase 3
HOXC6 homeobox C6
HSPA8 heat shock 70kDa protein 8
HTRA1 HtrA serine peptidase 1
ICAM2 intercellular adhesion molecule 2
IFI27 interferon, alpha-inducible protein 27
ITGAV integrin, alpha V
LAMC2 laminin, gamma 2
NFIB nuclear factor I/B
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NGRN neugrin, neurite outgrowth associated
NNMT nicotinamide N-methyltransferase
NOTCH2NL notch 2 N-terminal like
NPY neuropeptide Y
NR2F2 nuclear receptor subfamily 2, group F, member 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCDH9 protocadherin 9
PMEPA1 prostate transmembrane protein, androgen induced 1
PROM1 prominin 1
RECQL RecQ helicase-like
RPL37A ribosomal protein L37a
SELL selectin L
SEPW1 selenoprotein W, 1
SFN stratifin
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36
SRSF7 serine/arginine-rich splicing factor 7
TGFBI transforming growth factor, beta-induced, 68kDa
THBS4 thrombospondin 4
TMEM260 transmembrane protein 260
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
ZBTB20 zinc finger and BTB domain containing 20