BRD-K46556543_Canrenoic acid potassium salt_HCC515_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K46556543_Canrenoic acid potassium salt_HCC515_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ARG2 arginase 2
ASS1 argininosuccinate synthase 1
CD86 CD86 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHGB chromogranin B
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
CREB1 cAMP responsive element binding protein 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DENND1B DENN/MADD domain containing 1B
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EXT1 exostosin glycosyltransferase 1
FGL2 fibrinogen-like 2
GALC galactosylceramidase
GBP1 guanylate binding protein 1, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
HIST1H1C histone cluster 1, H1c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
INA internexin neuronal intermediate filament protein, alpha
INHBB inhibin, beta B
INSM1 insulinoma-associated 1
ITGA8 integrin, alpha 8
MAOA monoamine oxidase A
NR1H2 nuclear receptor subfamily 1, group H, member 2
P3H2 prolyl 3-hydroxylase 2
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PRUNE2 prune homolog 2 (Drosophila)
RAI14 retinoic acid induced 14
RGCC regulator of cell cycle
RNASE6 ribonuclease, RNase A family, k6
RND3 Rho family GTPase 3
SHB Src homology 2 domain containing adaptor protein B
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
STS steroid sulfatase (microsomal), isozyme S
TCTA T-cell leukemia translocation altered
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
UBE2J1 ubiquitin-conjugating enzyme E2, J1
VEGFA vascular endothelial growth factor A
VLDLR very low density lipoprotein receptor

decreased expression

Symbol Name
AGR2 anterior gradient 2
AREG amphiregulin
ATP9A ATPase, class II, type 9A
CXCL8 chemokine (C-X-C motif) ligand 8
DEFB1 defensin, beta 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSP desmoplakin
FAM171A1 family with sequence similarity 171, member A1
FOLR1 folate receptor 1 (adult)
GOLM1 golgi membrane protein 1
GRB14 growth factor receptor-bound protein 14
HN1 hematological and neurological expressed 1
HOMER1 homer scaffolding protein 1
HOXC6 homeobox C6
MARCKSL1 MARCKS-like 1
MSX1 msh homeobox 1
PCDH9 protocadherin 9
PPIF peptidylprolyl isomerase F
RAB40B RAB40B, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RPS11 ribosomal protein S11
RPS26 ribosomal protein S26
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SET SET nuclear proto-oncogene
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SORD sorbitol dehydrogenase
SOX9 SRY (sex determining region Y)-box 9
SRPX sushi-repeat containing protein, X-linked
TESC tescalcin
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TSPAN8 tetraspanin 8