BRD-K46056750_AZD-7762_PC3_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K46056750_AZD-7762_PC3_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AQP3 aquaporin 3 (Gill blood group)
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC2B C-type lectin domain family 2, member B
DENND2D DENN/MADD domain containing 2D
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FCGBP Fc fragment of IgG binding protein
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
HIST2H2BE histone cluster 2, H2be
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ITM2A integral membrane protein 2A
KIZ kizuna centrosomal protein
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAL mal, T-cell differentiation protein
PAN2 PAN2 poly(A) specific ribonuclease subunit
PBX1 pre-B-cell leukemia homeobox 1
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PNRC1 proline-rich nuclear receptor coactivator 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGCC regulator of cell cycle
RGS5 regulator of G-protein signaling 5
RHOBTB3 Rho-related BTB domain containing 3
S100P S100 calcium binding protein P
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRSF5 serine/arginine-rich splicing factor 5
TFF1 trefoil factor 1
TXNIP thioredoxin interacting protein
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
BICD2 bicaudal D homolog 2 (Drosophila)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CD52 CD52 molecule
CORO1C coronin, actin binding protein, 1C
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DEFB1 defensin, beta 1
EIF5A eukaryotic translation initiation factor 5A
EPB41L2 erythrocyte membrane protein band 4.1-like 2
FABP4 fatty acid binding protein 4, adipocyte
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
HMOX1 heme oxygenase 1
IGFBP3 insulin-like growth factor binding protein 3
INHBA inhibin, beta A
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
RBM3 RNA binding motif (RNP1, RRM) protein 3
RPN2 ribophorin II
SFN stratifin
TGFA transforming growth factor, alpha
VCAN versican
WIF1 WNT inhibitory factor 1
YME1L1 YME1-like 1 ATPase