BRD-K46056750_AZD-7762_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K46056750_AZD-7762_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
COL11A1 collagen, type XI, alpha 1
FOXF1 forkhead box F1
FXYD6 FXYD domain containing ion transport regulator 6
GAS1 growth arrest-specific 1
GOLM1 golgi membrane protein 1
GPM6B glycoprotein M6B
KDM3A lysine (K)-specific demethylase 3A
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MARCKS myristoylated alanine-rich protein kinase C substrate
MEIS2 Meis homeobox 2
OLFM4 olfactomedin 4
PDE4B phosphodiesterase 4B, cAMP-specific
PROM1 prominin 1
PTN pleiotrophin
PXMP2 peroxisomal membrane protein 2, 22kDa
RGL1 ral guanine nucleotide dissociation stimulator-like 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SST somatostatin
TSC22D3 TSC22 domain family, member 3
VAV3 vav 3 guanine nucleotide exchange factor
ZNF274 zinc finger protein 274

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRF5 adhesion G protein-coupled receptor F5
ADM adrenomedullin
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AQP3 aquaporin 3 (Gill blood group)
BGN biglycan
CCND1 cyclin D1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
EGR3 early growth response 3
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
ITM2A integral membrane protein 2A
KLF4 Kruppel-like factor 4 (gut)
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LPCAT1 lysophosphatidylcholine acyltransferase 1
MAL mal, T-cell differentiation protein
MALL mal, T-cell differentiation protein-like
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PODXL podocalyxin-like
PPL periplakin
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPEN spen family transcriptional repressor
SPRED2 sprouty-related, EVH1 domain containing 2
STEAP3 STEAP family member 3, metalloreductase
THBD thrombomodulin
TKT transketolase
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TPD52L1 tumor protein D52-like 1