BRD-K44878494_4-(5-amino-3-methyl-4-(3-(trifluoromethyl)benzoyl)thiophen-2-yl)butanoic acid KAJ-13_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

25 genes differentially expressed following the BRD-K44878494_4-(5-amino-3-methyl-4-(3-(trifluoromethyl)benzoyl)thiophen-2-yl)butanoic acid KAJ-13_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AEBP1 AE binding protein 1
ANGPTL2 angiopoietin-like 2
ARL4C ADP-ribosylation factor-like 4C
AURKB aurora kinase B
DKK3 dickkopf WNT signaling pathway inhibitor 3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
LAPTM5 lysosomal protein transmembrane 5
NPTX2 neuronal pentraxin II
PRKX protein kinase, X-linked

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
ANPEP alanyl (membrane) aminopeptidase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHPT1 choline phosphotransferase 1
CLCN3 chloride channel, voltage-sensitive 3
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DUSP1 dual specificity phosphatase 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GCLC glutamate-cysteine ligase, catalytic subunit
GLRX glutaredoxin (thioltransferase)
KRT7 keratin 7, type II
KYNU kynureninase
PDLIM5 PDZ and LIM domain 5
PLAC8 placenta-specific 8
TRAM1 translocation associated membrane protein 1