BRD-K43389698_BMS-387032_HME1_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

210 genes differentially expressed following the BRD-K43389698_BMS-387032_HME1_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACKR3 atypical chemokine receptor 3
ACP5 acid phosphatase 5, tartrate resistant
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANO1 anoctamin 1, calcium activated chloride channel
AQP1 aquaporin 1 (Colton blood group)
ATF3 activating transcription factor 3
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATXN1 ataxin 1
BEX1 brain expressed, X-linked 1
BHLHE40 basic helix-loop-helix family, member e40
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
CADM1 cell adhesion molecule 1
CCL20 chemokine (C-C motif) ligand 20
CD3D CD3d molecule, delta (CD3-TCR complex)
CD4 CD4 molecule
CD84 CD84 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CERS6 ceramide synthase 6
CFD complement factor D (adipsin)
CLEC11A C-type lectin domain family 11, member A
CLU clusterin
COG5 component of oligomeric golgi complex 5
COL11A1 collagen, type XI, alpha 1
CPE carboxypeptidase E
CREB1 cAMP responsive element binding protein 1
CTGF connective tissue growth factor
CTSB cathepsin B
CTSZ cathepsin Z
CXCL8 chemokine (C-X-C motif) ligand 8
CYB561 cytochrome b561
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DMXL2 Dmx-like 2
ECM1 extracellular matrix protein 1
EGR1 early growth response 1
EGR3 early growth response 3
EIF5A eukaryotic translation initiation factor 5A
ENO2 enolase 2 (gamma, neuronal)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ESR1 estrogen receptor 1
FABP6 fatty acid binding protein 6, ileal
FAM162A family with sequence similarity 162, member A
FLRT2 fibronectin leucine rich transmembrane protein 2
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FYB FYN binding protein
GADD45B growth arrest and DNA-damage-inducible, beta
GAP43 growth associated protein 43
GLIPR1 GLI pathogenesis-related 1
GLT8D2 glycosyltransferase 8 domain containing 2
GPM6A glycoprotein M6A
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRN granulin
HDAC9 histone deacetylase 9
HLA-DMA major histocompatibility complex, class II, DM alpha
HMOX1 heme oxygenase 1
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IDS iduronate 2-sulfatase
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
ITFG1 integrin alpha FG-GAP repeat containing 1
ITM2A integral membrane protein 2A
ITM2C integral membrane protein 2C
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KLF10 Kruppel-like factor 10
KRT19 keratin 19, type I
LEFTY1 left-right determination factor 1
LOC100505650 uncharacterized LOC100505650
LRRC17 leucine rich repeat containing 17
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAOA monoamine oxidase A
MATN2 matrilin 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLF1 myeloid leukemia factor 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP1 matrix metallopeptidase 1
MMP9 matrix metallopeptidase 9
MXI1 MAX interactor 1, dimerization protein
NDRG1 N-myc downstream regulated 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NUPR1 nuclear protein, transcriptional regulator, 1
PAWR PRKC, apoptosis, WT1, regulator
PCBP2 poly(rC) binding protein 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLBD1 phospholipase B domain containing 1
PPT1 palmitoyl-protein thioesterase 1
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCH protein kinase C, eta
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRO protein tyrosine phosphatase, receptor type, O
QPCT glutaminyl-peptide cyclotransferase
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RBP1 retinol binding protein 1, cellular
REG1A regenerating islet-derived 1 alpha
RGS5 regulator of G-protein signaling 5
RNASET2 ribonuclease T2
SATB2 SATB homeobox 2
SCG5 secretogranin V
SCGB2A1 secretoglobin, family 2A, member 1
SDC2 syndecan 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP4 secreted frizzled-related protein 4
SH2D1A SH2 domain containing 1A
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SMYD3 SET and MYND domain containing 3
SNX10 sorting nexin 10
SPON1 spondin 1, extracellular matrix protein
SST somatostatin
TFF3 trefoil factor 3 (intestinal)
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM123 transmembrane protein 123
TMEM45A transmembrane protein 45A
TMOD1 tropomodulin 1
TPD52 tumor protein D52
TPP1 tripeptidyl peptidase I
TRBC1 T cell receptor beta constant 1
TSPAN7 tetraspanin 7
TUSC3 tumor suppressor candidate 3
TYROBP TYRO protein tyrosine kinase binding protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VNN1 vanin 1
WIF1 WNT inhibitory factor 1
WT1 Wilms tumor 1
XIST X inactive specific transcript (non-protein coding)
ZFPM2 zinc finger protein, FOG family member 2
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
AGTR1 angiotensin II receptor, type 1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AUTS2 autism susceptibility candidate 2
BIN1 bridging integrator 1
C2CD5 C2 calcium-dependent domain containing 5
CA2 carbonic anhydrase II
CCNA2 cyclin A2
CCNB2 cyclin B2
CCNF cyclin F
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CENPA centromere protein A
CKS1B CDC28 protein kinase regulatory subunit 1B
CKS2 CDC28 protein kinase regulatory subunit 2
CSE1L CSE1 chromosome segregation 1-like (yeast)
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EFS embryonal Fyn-associated substrate
FSCN1 fascin actin-bundling protein 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GAS1 growth arrest-specific 1
HOXA5 homeobox A5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA8 heat shock 70kDa protein 8
IGFBP4 insulin-like growth factor binding protein 4
IGFBP6 insulin-like growth factor binding protein 6
KRT7 keratin 7, type II
LBR lamin B receptor
LTF lactotransferrin
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAT2A methionine adenosyltransferase II, alpha
MKI67 marker of proliferation Ki-67
MKNK2 MAP kinase interacting serine/threonine kinase 2
MRPL15 mitochondrial ribosomal protein L15
MYBPC1 myosin binding protein C, slow type
NFIB nuclear factor I/B
NPY1R neuropeptide Y receptor Y1
NUP62 nucleoporin 62kDa
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PCM1 pericentriolar material 1
PCNA proliferating cell nuclear antigen
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLK1 polo-like kinase 1
PNP purine nucleoside phosphorylase
POSTN periostin, osteoblast specific factor
PTMA prothymosin, alpha
PTX3 pentraxin 3, long
PXDN peroxidasin
RABGAP1 RAB GTPase activating protein 1
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SPINK1 serine peptidase inhibitor, Kazal type 1
STOM stomatin
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TOP2A topoisomerase (DNA) II alpha 170kDa
TRAM2 translocation associated membrane protein 2
TUBB3 tubulin, beta 3 class III
TUBB6 tubulin, beta 6 class V
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S