BRD-K43389698_BMS-387032_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K43389698_BMS-387032_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
DPYSL2 dihydropyrimidinase-like 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5A eukaryotic translation initiation factor 5A
FGFR3 fibroblast growth factor receptor 3
GAS6 growth arrest-specific 6
GOLM1 golgi membrane protein 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H1C histone cluster 1, H1c
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGFBP5 insulin-like growth factor binding protein 5
ISG15 ISG15 ubiquitin-like modifier
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0226L KIAA0226-like
LEPR leptin receptor
LYN LYN proto-oncogene, Src family tyrosine kinase
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PEG3 paternally expressed 3
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PLA2G16 phospholipase A2, group XVI
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PRUNE2 prune homolog 2 (Drosophila)
PXDN peroxidasin
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC2 syndecan 2
SEPW1 selenoprotein W, 1
SFRP1 secreted frizzled-related protein 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SORBS1 sorbin and SH3 domain containing 1
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
TMEM47 transmembrane protein 47
TNS1 tensin 1
TUBA1A tubulin, alpha 1a
UGP2 UDP-glucose pyrophosphorylase 2
VWA5A von Willebrand factor A domain containing 5A

decreased expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AHR aryl hydrocarbon receptor
APOLD1 apolipoprotein L domain containing 1
ARID4B AT rich interactive domain 4B (RBP1-like)
BAMBI BMP and activin membrane-bound inhibitor
BCL10 B-cell CLL/lymphoma 10
BEX4 brain expressed, X-linked 4
BTG2 BTG family, member 2
C8ORF4 chromosome 8 open reading frame 4
CCNE1 cyclin E1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC25A cell division cycle 25A
CHD7 chromodomain helicase DNA binding protein 7
CLU clusterin
CXCL14 chemokine (C-X-C motif) ligand 14
DUSP5 dual specificity phosphatase 5
EGR2 early growth response 2
EGR3 early growth response 3
FOSL1 FOS-like antigen 1
FZD7 frizzled class receptor 7
GADD45B growth arrest and DNA-damage-inducible, beta
GCH1 GTP cyclohydrolase 1
GEM GTP binding protein overexpressed in skeletal muscle
HES1 hes family bHLH transcription factor 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IER3 immediate early response 3
IER5 immediate early response 5
JUNB jun B proto-oncogene
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NRIP1 nuclear receptor interacting protein 1
PER2 period circadian clock 2
PLK2 polo-like kinase 2
RIPK4 receptor-interacting serine-threonine kinase 4
SERTAD2 SERTA domain containing 2
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY2 sprouty homolog 2 (Drosophila)
TBP TATA box binding protein
WEE1 WEE1 G2 checkpoint kinase
ZFP36 ZFP36 ring finger protein
ZFP36L2 ZFP36 ring finger protein-like 2