BRD-K43068349_AMG 9810_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-K43068349_AMG 9810_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CA2 carbonic anhydrase II
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EREG epiregulin
FAM129A family with sequence similarity 129, member A
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
NID1 nidogen 1
PDE4B phosphodiesterase 4B, cAMP-specific
RGCC regulator of cell cycle
SIK1 salt-inducible kinase 1
SULF1 sulfatase 1

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACLY ATP citrate lyase
CD36 CD36 molecule (thrombospondin receptor)
CYBA cytochrome b-245, alpha polypeptide
EMP3 epithelial membrane protein 3
EVL Enah/Vasp-like
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GPC3 glypican 3
HES1 hes family bHLH transcription factor 1
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
INSIG1 insulin induced gene 1
LTF lactotransferrin
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SRSF5 serine/arginine-rich splicing factor 5
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TMC5 transmembrane channel-like 5
TSPAN8 tetraspanin 8