BRD-K42805893_HG-14-8-02_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-K42805893_HG-14-8-02_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADCY1 adenylate cyclase 1 (brain)
AKR1C2 aldo-keto reductase family 1, member C2
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCNB1 cyclin B1
CD200 CD200 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DEFA5 defensin, alpha 5, Paneth cell-specific
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
E2F2 E2F transcription factor 2
EDNRB endothelin receptor type B
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FBLN1 fibulin 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
IFRD2 interferon-related developmental regulator 2
KCTD14 potassium channel tetramerization domain containing 14
L1CAM L1 cell adhesion molecule
LEF1 lymphoid enhancer-binding factor 1
LPAR6 lysophosphatidic acid receptor 6
LXN latexin
MAN1A1 mannosidase, alpha, class 1A, member 1
MATN2 matrilin 2
MMP12 matrix metallopeptidase 12
MMP3 matrix metallopeptidase 3
MYLK myosin light chain kinase
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NTS neurotensin
OLFM4 olfactomedin 4
PCP4 Purkinje cell protein 4
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PMP22 peripheral myelin protein 22
POSTN periostin, osteoblast specific factor
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
REG1A regenerating islet-derived 1 alpha
REG1B regenerating islet-derived 1 beta
RHOBTB3 Rho-related BTB domain containing 3
RSAD2 radical S-adenosyl methionine domain containing 2
SELENBP1 selenium binding protein 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOX4 SRY (sex determining region Y)-box 4
TBX3 T-box 3
TFF1 trefoil factor 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNC tenascin C
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
XIST X inactive specific transcript (non-protein coding)
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
ACSL1 acyl-CoA synthetase long-chain family member 1
APMAP adipocyte plasma membrane associated protein
BASP1 brain abundant, membrane attached signal protein 1
BLNK B-cell linker
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CST6 cystatin E/M
DEGS1 delta(4)-desaturase, sphingolipid 1
F2R coagulation factor II (thrombin) receptor
FGG fibrinogen gamma chain
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOPX HOP homeobox
HOXB2 homeobox B2
KLK6 kallikrein-related peptidase 6
MYO6 myosin VI
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NRN1 neuritin 1
PDGFC platelet derived growth factor C
PHLDA2 pleckstrin homology-like domain, family A, member 2
PNP purine nucleoside phosphorylase
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC35F2 solute carrier family 35, member F2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
TAGLN2 transgelin 2
TM9SF3 transmembrane 9 superfamily member 3
TPD52 tumor protein D52
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
VDAC1 voltage-dependent anion channel 1
VWF von Willebrand factor