BRD-K41895714_AS-605240_HT29_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

137 genes differentially expressed following the BRD-K41895714_AS-605240_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACSF2 acyl-CoA synthetase family member 2
ADD3 adducin 3 (gamma)
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
AMACR alpha-methylacyl-CoA racemase
ANXA4 annexin A4
ATP9A ATPase, class II, type 9A
AUTS2 autism susceptibility candidate 2
AZU1 azurocidin 1
BASP1 brain abundant, membrane attached signal protein 1
BECN1 beclin 1, autophagy related
BLNK B-cell linker
CCDC92 coiled-coil domain containing 92
CELF2 CUGBP, Elav-like family member 2
CFD complement factor D (adipsin)
CLCA1 chloride channel accessory 1
CPA3 carboxypeptidase A3 (mast cell)
CPT1A carnitine palmitoyltransferase 1A (liver)
CST3 cystatin C
CTSG cathepsin G
CXCL14 chemokine (C-X-C motif) ligand 14
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
F13A1 coagulation factor XIII, A1 polypeptide
FAM134B family with sequence similarity 134, member B
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOLR1 folate receptor 1 (adult)
FOXO4 forkhead box O4
GAB2 GRB2-associated binding protein 2
GHR growth hormone receptor
GLS glutaminase
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GOLGA8H golgin A8 family, member H
GRN granulin
HES1 hes family bHLH transcription factor 1
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IPO13 importin 13
ISG15 ISG15 ubiquitin-like modifier
ITM2C integral membrane protein 2C
JCHAIN joining chain of multimeric IgA and IgM
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KRT20 keratin 20, type I
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGED1 melanoma antigen family D1
MAOA monoamine oxidase A
MFAP5 microfibrillar associated protein 5
MME membrane metallo-endopeptidase
MVP major vault protein
MYLK myosin light chain kinase
NDRG1 N-myc downstream regulated 1
NEFL neurofilament, light polypeptide
NIPSNAP1 nipsnap homolog 1 (C. elegans)
PBLD phenazine biosynthesis-like protein domain containing
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDGFRL platelet-derived growth factor receptor-like
PDZK1IP1 PDZK1 interacting protein 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
QPRT quinolinate phosphoribosyltransferase
RABAC1 Rab acceptor 1 (prenylated)
REG1A regenerating islet-derived 1 alpha
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A1 secretoglobin, family 2A, member 1
SEPP1 selenoprotein P, plasma, 1
SESN1 sestrin 1
SH3BGRL SH3 domain binding glutamate-rich protein like
SI sucrase-isomaltase (alpha-glucosidase)
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX4 SRY (sex determining region Y)-box 4
SPATA20 spermatogenesis associated 20
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SST somatostatin
TCF4 transcription factor 4
TFF1 trefoil factor 1
TOX3 TOX high mobility group box family member 3
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TST thiosulfate sulfurtransferase (rhodanese)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ADAM9 ADAM metallopeptidase domain 9
ADM adrenomedullin
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMD1 adenosylmethionine decarboxylase 1
ANXA2 annexin A2
ANXA2P2 annexin A2 pseudogene 2
APOA2 apolipoprotein A-II
BIRC5 baculoviral IAP repeat containing 5
CCNA2 cyclin A2
CDC25A cell division cycle 25A
CDK1 cyclin-dependent kinase 1
CENPU centromere protein U
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL5A1 collagen, type V, alpha 1
CRIP2 cysteine-rich protein 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP5 dual specificity phosphatase 5
EGR2 early growth response 2
EIF5A eukaryotic translation initiation factor 5A
EMP1 epithelial membrane protein 1
ENO1 enolase 1, (alpha)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOSL1 FOS-like antigen 1
GAL galanin/GMAP prepropeptide
HMGB2 high mobility group box 2
HPRT1 hypoxanthine phosphoribosyltransferase 1
IER3 immediate early response 3
INPP1 inositol polyphosphate-1-phosphatase
LYPLA1 lysophospholipase I
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NES nestin
NOLC1 nucleolar and coiled-body phosphoprotein 1
NPY1R neuropeptide Y receptor Y1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PDE4B phosphodiesterase 4B, cAMP-specific
PHLDA1 pleckstrin homology-like domain, family A, member 1
PNP purine nucleoside phosphorylase
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRC1 protein regulator of cytokinesis 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RTN1 reticulon 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
TF transferrin
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
UBE2S ubiquitin-conjugating enzyme E2S
UPP1 uridine phosphorylase 1
WEE1 WEE1 G2 checkpoint kinase