BRD-K41895714_AS-605240_HME1_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

132 genes differentially expressed following the BRD-K41895714_AS-605240_HME1_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ATF3 activating transcription factor 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CLU clusterin
CRYAB crystallin, alpha B
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DST dystonin
FRS2 fibroblast growth factor receptor substrate 2
FZD2 frizzled class receptor 2
GADD45B growth arrest and DNA-damage-inducible, beta
GLUL glutamate-ammonia ligase
HCAR3 hydroxycarboxylic acid receptor 3
HMG20B high mobility group 20B
HOXA10 homeobox A10
HSPB8 heat shock 22kDa protein 8
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
MAB21L1 mab-21-like 1 (C. elegans)
MAN1C1 mannosidase, alpha, class 1C, member 1
MEIS2 Meis homeobox 2
MMP7 matrix metallopeptidase 7
MOXD1 monooxygenase, DBH-like 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NUPR1 nuclear protein, transcriptional regulator, 1
OSR2 odd-skipped related transciption factor 2
OXTR oxytocin receptor
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PAX6 paired box 6
PBX1 pre-B-cell leukemia homeobox 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
RAD23B RAD23 homolog B (S. cerevisiae)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SCYL3 SCY1-like 3 (S. cerevisiae)
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SNCAIP synuclein, alpha interacting protein
SOD2 superoxide dismutase 2, mitochondrial
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM16 tripartite motif containing 16
VAMP4 vesicle-associated membrane protein 4
ZIC1 Zic family member 1

decreased expression

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADD3 adducin 3 (gamma)
ADGRL2 adhesion G protein-coupled receptor L2
ALCAM activated leukocyte cell adhesion molecule
AREG amphiregulin
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARL4C ADP-ribosylation factor-like 4C
ASCL1 achaete-scute family bHLH transcription factor 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BICC1 BicC family RNA binding protein 1
C3ORF14 chromosome 3 open reading frame 14
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHIC2 cysteine-rich hydrophobic domain 2
CKLF chemokine-like factor
CPE carboxypeptidase E
CRIP1 cysteine-rich protein 1 (intestinal)
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHCR24 24-dehydrocholesterol reductase
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPCAM epithelial cell adhesion molecule
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FOSL1 FOS-like antigen 1
HBEGF heparin-binding EGF-like growth factor
HLA-DRA major histocompatibility complex, class II, DR alpha
HMGA2 high mobility group AT-hook 2
IER3 immediate early response 3
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IL1B interleukin 1, beta
IL6 interleukin 6
JAG1 jagged 1
KDM5D lysine (K)-specific demethylase 5D
LDLR low density lipoprotein receptor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP1 matrix metallopeptidase 1
MSMO1 methylsterol monooxygenase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH11 myosin, heavy chain 11, smooth muscle
NR4A2 nuclear receptor subfamily 4, group A, member 2
NT5E 5'-nucleotidase, ecto (CD73)
ODC1 ornithine decarboxylase 1
OSBPL10 oxysterol binding protein-like 10
PCLO piccolo presynaptic cytomatrix protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAT plasminogen activator, tissue
PNP purine nucleoside phosphorylase
POSTN periostin, osteoblast specific factor
PRR15L proline rich 15-like
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPRO protein tyrosine phosphatase, receptor type, O
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SC5D sterol-C5-desaturase
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SOX9 SRY (sex determining region Y)-box 9
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SRGN serglycin
STC1 stanniocalcin 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
TFPI2 tissue factor pathway inhibitor 2
TGFA transforming growth factor, alpha
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBD thrombomodulin
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TM4SF1 transmembrane 4 L six family member 1
TMEM30B transmembrane protein 30B
TRIB2 tribbles pseudokinase 2
TUSC3 tumor suppressor candidate 3
WWTR1 WW domain containing transcription regulator 1