BRD-K40175214_torin-1_MCF7_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

112 genes differentially expressed following the BRD-K40175214_torin-1_MCF7_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABHD4 abhydrolase domain containing 4
ANXA1 annexin A1
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG1 B-cell translocation gene 1, anti-proliferative
C10ORF10 chromosome 10 open reading frame 10
CCNG2 cyclin G2
CD44 CD44 molecule (Indian blood group)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CENPE centromere protein E, 312kDa
DHRS3 dehydrogenase/reductase (SDR family) member 3
DMXL2 Dmx-like 2
DUSP6 dual specificity phosphatase 6
FAM13A family with sequence similarity 13, member A
FBN2 fibrillin 2
GADD45B growth arrest and DNA-damage-inducible, beta
GULP1 GULP, engulfment adaptor PTB domain containing 1
HBP1 HMG-box transcription factor 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HOXB6 homeobox B6
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
JMJD1C jumonji domain containing 1C
KDM3A lysine (K)-specific demethylase 3A
KDM5A lysine (K)-specific demethylase 5A
KIF14 kinesin family member 14
KLF7 Kruppel-like factor 7 (ubiquitous)
LYN LYN proto-oncogene, Src family tyrosine kinase
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MX2 MX dynamin-like GTPase 2
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO6 myosin VI
N4BP2L2 NEDD4 binding protein 2-like 2
NEFL neurofilament, light polypeptide
NOV nephroblastoma overexpressed
NRIP1 nuclear receptor interacting protein 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PDGFRL platelet-derived growth factor receptor-like
PEG10 paternally expressed 10
PILRB paired immunoglobin-like type 2 receptor beta
PTPRK protein tyrosine phosphatase, receptor type, K
RGS2 regulator of G-protein signaling 2
RSRP1 arginine/serine-rich protein 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SGCE sarcoglycan, epsilon
SLC35F2 solute carrier family 35, member F2
SLPI secretory leukocyte peptidase inhibitor
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SYBU syntabulin (syntaxin-interacting)
TGFBI transforming growth factor, beta-induced, 68kDa
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPBG trophoblast glycoprotein
TRA2A transformer 2 alpha homolog (Drosophila)
TSC22D3 TSC22 domain family, member 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VIM vimentin
VTCN1 V-set domain containing T cell activation inhibitor 1
WSB1 WD repeat and SOCS box containing 1
ZNF292 zinc finger protein 292

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTA2 actin, alpha 2, smooth muscle, aorta
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ARPP19 cAMP-regulated phosphoprotein, 19kDa
B3GNT1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAPN1 calpain 1, (mu/I) large subunit
CCND1 cyclin D1
CDC25A cell division cycle 25A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
COL3A1 collagen, type III, alpha 1
CYR61 cysteine-rich, angiogenic inducer, 61
FAM57A family with sequence similarity 57, member A
FAS Fas cell surface death receptor
GATA2 GATA binding protein 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HSPH1 heat shock 105kDa/110kDa protein 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LEPROTL1 leptin receptor overlapping transcript-like 1
MAT2A methionine adenosyltransferase II, alpha
MMP12 matrix metallopeptidase 12
MYLK myosin light chain kinase
PHLDA2 pleckstrin homology-like domain, family A, member 2
PMP22 peripheral myelin protein 22
PRKCB protein kinase C, beta
PTGDS prostaglandin D2 synthase 21kDa (brain)
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A10 S100 calcium binding protein A10
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SFN stratifin
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SPP1 secreted phosphoprotein 1
TGM2 transglutaminase 2
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1