BRD-K40175214_torin-1_LNCAP_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K40175214_torin-1_LNCAP_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCK3 aarF domain containing kinase 3
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
ARG2 arginase 2
ARID5B AT rich interactive domain 5B (MRF1-like)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DCN decorin
DLK1 delta-like 1 homolog (Drosophila)
DPP4 dipeptidyl-peptidase 4
GADD45A growth arrest and DNA-damage-inducible, alpha
GBP2 guanylate binding protein 2, interferon-inducible
GPATCH8 G patch domain containing 8
IL6ST interleukin 6 signal transducer
KLHL21 kelch-like family member 21
NBR1 neighbor of BRCA1 gene 1
NPC1 Niemann-Pick disease, type C1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEG3 paternally expressed 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAT plasminogen activator, tissue
PPAP2B phosphatidic acid phosphatase type 2B
RPL36 ribosomal protein L36
SERINC5 serine incorporator 5
SFRP1 secreted frizzled-related protein 1
SNX10 sorting nexin 10
SPARCL1 SPARC-like 1 (hevin)
SPP1 secreted phosphoprotein 1
SRPX sushi-repeat containing protein, X-linked
STON1 stonin 1
SYNM synemin, intermediate filament protein
TLR4 toll-like receptor 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52 tumor protein D52
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ANXA3 annexin A3
AREG amphiregulin
CDC25A cell division cycle 25A
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
DDIT4 DNA-damage-inducible transcript 4
EFNB2 ephrin-B2
FKBP1B FK506 binding protein 1B, 12.6 kDa
GSTP1 glutathione S-transferase pi 1
HBEGF heparin-binding EGF-like growth factor
HIC2 hypermethylated in cancer 2
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
KIAA0101 KIAA0101
MAT2A methionine adenosyltransferase II, alpha
NR4A2 nuclear receptor subfamily 4, group A, member 2
PLK2 polo-like kinase 2
PON2 paraoxonase 2
PSPH phosphoserine phosphatase
RPL31 ribosomal protein L31
SIK1 salt-inducible kinase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TCF4 transcription factor 4
TPBG trophoblast glycoprotein
TXNDC9 thioredoxin domain containing 9
VCAM1 vascular cell adhesion molecule 1
WFDC2 WAP four-disulfide core domain 2