BRD-K40175214_torin-1_HME1_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

118 genes differentially expressed following the BRD-K40175214_torin-1_HME1_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARID5B AT rich interactive domain 5B (MRF1-like)
ATF3 activating transcription factor 3
BCL2A1 BCL2-related protein A1
BIRC2 baculoviral IAP repeat containing 2
C10ORF10 chromosome 10 open reading frame 10
C7 complement component 7
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEMIP cell migration inducing protein, hyaluronan binding
CHIC2 cysteine-rich hydrophobic domain 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLC Charcot-Leyden crystal galectin
CLDN4 claudin 4
COBL cordon-bleu WH2 repeat protein
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DST dystonin
DUSP6 dual specificity phosphatase 6
EFNB2 ephrin-B2
EIF5 eukaryotic translation initiation factor 5
ELF5 E74-like factor 5 (ets domain transcription factor)
ERBB4 erb-b2 receptor tyrosine kinase 4
FAM129A family with sequence similarity 129, member A
FAM13A family with sequence similarity 13, member A
FLNA filamin A, alpha
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GMDS GDP-mannose 4,6-dehydratase
HBP1 HMG-box transcription factor 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFRD1 interferon-related developmental regulator 1
IGF1R insulin-like growth factor 1 receptor
KIF14 kinesin family member 14
KLHL21 kelch-like family member 21
KRT81 keratin 81, type II
LETMD1 LETM1 domain containing 1
LIMCH1 LIM and calponin homology domains 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MCOLN1 mucolipin 1
MET MET proto-oncogene, receptor tyrosine kinase
MPPED2 metallophosphoesterase domain containing 2
NBPF10 neuroblastoma breakpoint family, member 10
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NR2F1 nuclear receptor subfamily 2, group F, member 1
NUPR1 nuclear protein, transcriptional regulator, 1
OXTR oxytocin receptor
PLAT plasminogen activator, tissue
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PRKCH protein kinase C, eta
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RSRP1 arginine/serine-rich protein 1
SLC35E2B solute carrier family 35, member E2B
STX1A syntaxin 1A (brain)
TBX2 T-box 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TM4SF1 transmembrane 4 L six family member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TREM1 triggering receptor expressed on myeloid cells 1
TSC22D3 TSC22 domain family, member 3
ZNF277 zinc finger protein 277

decreased expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
CALML3 calmodulin-like 3
CCND1 cyclin D1
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CRABP2 cellular retinoic acid binding protein 2
CRIP1 cysteine-rich protein 1 (intestinal)
CRNN cornulin
CTSZ cathepsin Z
DDIT4 DNA-damage-inducible transcript 4
DERA deoxyribose-phosphate aldolase (putative)
DHCR24 24-dehydrocholesterol reductase
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGA fibrinogen alpha chain
FN1 fibronectin 1
GJA1 gap junction protein, alpha 1, 43kDa
GSTA1 glutathione S-transferase alpha 1
HHEX hematopoietically expressed homeobox
HSPA1A heat shock 70kDa protein 1A
JMJD6 jumonji domain containing 6
KLK13 kallikrein-related peptidase 13
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
LAPTM4B lysosomal protein transmembrane 4 beta
LOC283683 uncharacterized LOC283683
MAT2A methionine adenosyltransferase II, alpha
MTSS1 metastasis suppressor 1
MXRA7 matrix-remodelling associated 7
NDN necdin, melanoma antigen (MAGE) family member
NEFH neurofilament, heavy polypeptide
NNMT nicotinamide N-methyltransferase
PI3 peptidase inhibitor 3, skin-derived
PTPRE protein tyrosine phosphatase, receptor type, E
QPCT glutaminyl-peptide cyclotransferase
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SPRR1A small proline-rich protein 1A
SPRR2B small proline-rich protein 2B
TMEM70 transmembrane protein 70
TMSB15A thymosin beta 15a
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1