BRD-K40087974_2-chloro-N-{3-cyano-4-[(4-methoxyphenyl)sulfanyl]phenyl}benzenecarboxamide_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

23 genes differentially expressed following the BRD-K40087974_2-chloro-N-{3-cyano-4-[(4-methoxyphenyl)sulfanyl]phenyl}benzenecarboxamide_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACLY ATP citrate lyase
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
CBR3 carbonyl reductase 3
CCNA2 cyclin A2
CCND1 cyclin D1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
HOXC6 homeobox C6
PLK1 polo-like kinase 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2

decreased expression

Symbol Name
CORO1A coronin, actin binding protein, 1A
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
G0S2 G0/G1 switch 2
IFI16 interferon, gamma-inducible protein 16
KIAA0196 KIAA0196
LRRC17 leucine rich repeat containing 17
PEG10 paternally expressed 10
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RFTN1 raftlin, lipid raft linker 1
SDC1 syndecan 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFPI2 tissue factor pathway inhibitor 2
XIST X inactive specific transcript (non-protein coding)