BRD-K39829853_-666_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

28 genes differentially expressed following the BRD-K39829853_-666_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOA aldolase A, fructose-bisphosphate
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BACE2 beta-site APP-cleaving enzyme 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
COL11A1 collagen, type XI, alpha 1
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
KDM3A lysine (K)-specific demethylase 3A
MAN1A1 mannosidase, alpha, class 1A, member 1
MFSD10 major facilitator superfamily domain containing 10
RGS1 regulator of G-protein signaling 1
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
VGLL4 vestigial-like family member 4

decreased expression

Symbol Name
CTSH cathepsin H
CXCL12 chemokine (C-X-C motif) ligand 12
FABP4 fatty acid binding protein 4, adipocyte
G0S2 G0/G1 switch 2
HEBP1 heme binding protein 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HNMT histamine N-methyltransferase
P3H2 prolyl 3-hydroxylase 2
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1