BRD-K39829853_-666_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

41 genes differentially expressed following the BRD-K39829853_-666_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
AREG amphiregulin
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
BEX1 brain expressed, X-linked 1
CBS cystathionine-beta-synthase
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
DDIT4 DNA-damage-inducible transcript 4
GADD45A growth arrest and DNA-damage-inducible, alpha
GDF15 growth differentiation factor 15
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
IDO1 indoleamine 2,3-dioxygenase 1
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
ORM1 orosomucoid 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCG5 secretogranin V
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
STC2 stanniocalcin 2
TRIB3 tribbles pseudokinase 3

decreased expression

Symbol Name
CBR3 carbonyl reductase 3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FEN1 flap structure-specific endonuclease 1
H2AFX H2A histone family, member X
HSPB8 heat shock 22kDa protein 8
KIF20A kinesin family member 20A
MACF1 microtubule-actin crosslinking factor 1
MCM10 minichromosome maintenance complex component 10
PLEKHJ1 pleckstrin homology domain containing, family J member 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
RGS2 regulator of G-protein signaling 2
TAGLN2 transgelin 2
WWTR1 WW domain containing transcription regulator 1