BRD-K39829853_-666_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-K39829853_-666_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCY1 adenylate cyclase 1 (brain)
ADM adrenomedullin
AK4 adenylate kinase 4
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
BEX1 brain expressed, X-linked 1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTN3A2 butyrophilin, subfamily 3, member A2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHI3L2 chitinase 3-like 2
CLIC4 chloride intracellular channel 4
COBL cordon-bleu WH2 repeat protein
CXCL8 chemokine (C-X-C motif) ligand 8
DIO2 deiodinase, iodothyronine, type II
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENO2 enolase 2 (gamma, neuronal)
GBE1 glucan (1,4-alpha-), branching enzyme 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IQCG IQ motif containing G
JMJD6 jumonji domain containing 6
LBH limb bud and heart development
LOX lysyl oxidase
MXI1 MAX interactor 1, dimerization protein
NPY neuropeptide Y
NUPL1 nucleoporin like 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PFKP phosphofructokinase, platelet
PGK1 phosphoglycerate kinase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PON2 paraoxonase 2
PROM1 prominin 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS4 regulator of G-protein signaling 4
S100A7 S100 calcium binding protein A7
SH3YL1 SH3 and SYLF domain containing 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SORD sorbitol dehydrogenase
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBI transforming growth factor, beta-induced, 68kDa
VEGFA vascular endothelial growth factor A
WDR45B WD repeat domain 45B

decreased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
ADIRF adipogenesis regulatory factor
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
AURKB aurora kinase B
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCRL2 chemokine (C-C motif) receptor-like 2
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD93 CD93 molecule
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLC Charcot-Leyden crystal galectin
CLEC2B C-type lectin domain family 2, member B
CORO1A coronin, actin binding protein, 1A
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
CRABP1 cellular retinoic acid binding protein 1
CREB1 cAMP responsive element binding protein 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DACH1 dachshund family transcription factor 1
DENND1B DENN/MADD domain containing 1B
ERBB4 erb-b2 receptor tyrosine kinase 4
FBN2 fibrillin 2
FRZB frizzled-related protein
FST follistatin
GCG glucagon
GPNMB glycoprotein (transmembrane) nmb
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HNMT histamine N-methyltransferase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1B interleukin 1, beta
KRT13 keratin 13, type I
LPCAT1 lysophosphatidylcholine acyltransferase 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MFAP2 microfibrillar-associated protein 2
MUC2 mucin 2, oligomeric mucus/gel-forming
MX2 MX dynamin-like GTPase 2
NELL2 NEL-like 2 (chicken)
NRG1 neuregulin 1
OLFM4 olfactomedin 4
PBX1 pre-B-cell leukemia homeobox 1
PTPRO protein tyrosine phosphatase, receptor type, O
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RGS5 regulator of G-protein signaling 5
RPS4Y1 ribosomal protein S4, Y-linked 1
SCGB1D2 secretoglobin, family 1D, member 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEPP1 selenoprotein P, plasma, 1
SNX7 sorting nexin 7
SST somatostatin
STON1 stonin 1
SULF1 sulfatase 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
THBS1 thrombospondin 1
TMEM176B transmembrane protein 176B
TSPAN4 tetraspanin 4
WT1 Wilms tumor 1
ZNF586 zinc finger protein 586