BRD-K39757396_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-K39757396_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADAM12 ADAM metallopeptidase domain 12
ADM adrenomedullin
ATF3 activating transcription factor 3
BAMBI BMP and activin membrane-bound inhibitor
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C10ORF10 chromosome 10 open reading frame 10
CA12 carbonic anhydrase XII
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
DDIT4 DNA-damage-inducible transcript 4
DFNA5 deafness, autosomal dominant 5
DUSP5 dual specificity phosphatase 5
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FOSL1 FOS-like antigen 1
GCLC glutamate-cysteine ligase, catalytic subunit
HILPDA hypoxia inducible lipid droplet-associated
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
KDM3A lysine (K)-specific demethylase 3A
KLF9 Kruppel-like factor 9
LOX lysyl oxidase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MT1E metallothionein 1E
MT1M metallothionein 1M
NOX4 NADPH oxidase 4
NT5E 5'-nucleotidase, ecto (CD73)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP1 secreted frizzled-related protein 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC38A1 solute carrier family 38, member 1
SOD2 superoxide dismutase 2, mitochondrial
STC1 stanniocalcin 1
STC2 stanniocalcin 2
TFPI2 tissue factor pathway inhibitor 2
TGIF1 TGFB-induced factor homeobox 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TUSC3 tumor suppressor candidate 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VEGFA vascular endothelial growth factor A
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
AZU1 azurocidin 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFD complement factor D (adipsin)
CLU clusterin
CTSG cathepsin G
CXCL12 chemokine (C-X-C motif) ligand 12
DMD dystrophin
ELANE elastase, neutrophil expressed
EPHA3 EPH receptor A3
FAM46A family with sequence similarity 46, member A
FOLR1 folate receptor 1 (adult)
FYB FYN binding protein
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
HBB hemoglobin, beta
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISG15 ISG15 ubiquitin-like modifier
LEPR leptin receptor
LPCAT1 lysophosphatidylcholine acyltransferase 1
LYST lysosomal trafficking regulator
NR2F1 nuclear receptor subfamily 2, group F, member 1
QPRT quinolinate phosphoribosyltransferase
RNASE3 ribonuclease, RNase A family, 3
S100A7 S100 calcium binding protein A7
S100P S100 calcium binding protein P
SLPI secretory leukocyte peptidase inhibitor
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
STAT1 signal transducer and activator of transcription 1, 91kDa
TARP TCR gamma alternate reading frame protein
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
VAT1 vesicle amine transport 1
VCAM1 vascular cell adhesion molecule 1