BRD-K38340366_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-K38340366_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARG1 arginase 1
BTK Bruton agammaglobulinemia tyrosine kinase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL5 chemokine (C-C motif) ligand 5
CD9 CD9 molecule
COPS7A COP9 signalosome subunit 7A
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HP haptoglobin
IGFBP4 insulin-like growth factor binding protein 4
KIF20A kinesin family member 20A
KLRK1 killer cell lectin-like receptor subfamily K, member 1
MTCL1 microtubule crosslinking factor 1
NEB nebulin
NNMT nicotinamide N-methyltransferase
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PTN pleiotrophin
SIK1 salt-inducible kinase 1
TNS3 tensin 3
TST thiosulfate sulfurtransferase (rhodanese)
TTN titin
ZNF131 zinc finger protein 131

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA1 annexin A1
AQP3 aquaporin 3 (Gill blood group)
ATF3 activating transcription factor 3
CCND2 cyclin D2
CFB complement factor B
CFD complement factor D (adipsin)
CSTA cystatin A (stefin A)
CTSC cathepsin C
CYCS cytochrome c, somatic
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FGFR2 fibroblast growth factor receptor 2
FILIP1L filamin A interacting protein 1-like
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KCTD12 potassium channel tetramerization domain containing 12
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
REG1A regenerating islet-derived 1 alpha
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAP30 Sin3A-associated protein, 30kDa
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SETBP1 SET binding protein 1
SMAGP small cell adhesion glycoprotein
SOAT1 sterol O-acyltransferase 1
TFPI2 tissue factor pathway inhibitor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TSEN2 TSEN2 tRNA splicing endonuclease subunit
VCAN versican
YAP1 Yes-associated protein 1