BRD-K38012662_2-bromo-N-[3-(propionylamino)phenyl]benzamide_A375_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-K38012662_2-bromo-N-[3-(propionylamino)phenyl]benzamide_A375_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLU clusterin
DOK5 docking protein 5
DUSP22 dual specificity phosphatase 22
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EIF5B eukaryotic translation initiation factor 5B
ELANE elastase, neutrophil expressed
ESR1 estrogen receptor 1
F5 coagulation factor V (proaccelerin, labile factor)
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
H1F0 H1 histone family, member 0
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KRT7 keratin 7, type II
LEF1 lymphoid enhancer-binding factor 1
LIMS1 LIM and senescent cell antigen-like domains 1
MAMLD1 mastermind-like domain containing 1
MTSS1 metastasis suppressor 1
NTS neurotensin
PDLIM5 PDZ and LIM domain 5
PHYH phytanoyl-CoA 2-hydroxylase
RRAGD Ras-related GTP binding D
SCRG1 stimulator of chondrogenesis 1
SEPP1 selenoprotein P, plasma, 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
THBD thrombomodulin
TNC tenascin C
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPD52L1 tumor protein D52-like 1
VAMP8 vesicle-associated membrane protein 8
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACTG2 actin, gamma 2, smooth muscle, enteric
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALCAM activated leukocyte cell adhesion molecule
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
C8ORF4 chromosome 8 open reading frame 4
CADM1 cell adhesion molecule 1
CD36 CD36 molecule (thrombospondin receptor)
COCH cochlin
COL3A1 collagen, type III, alpha 1
CTSK cathepsin K
DCN decorin
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL2 dihydropyrimidinase-like 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EXPH5 exophilin 5
FABP4 fatty acid binding protein 4, adipocyte
FASN fatty acid synthase
FBLN1 fibulin 1
FILIP1L filamin A interacting protein 1-like
FN1 fibronectin 1
FSD1 fibronectin type III and SPRY domain containing 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
GREM1 gremlin 1, DAN family BMP antagonist
HBB hemoglobin, beta
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPH1 heat shock 105kDa/110kDa protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
LIMCH1 LIM and calponin homology domains 1
LPAR1 lysophosphatidic acid receptor 1
LY6E lymphocyte antigen 6 complex, locus E
MAOA monoamine oxidase A
MMD monocyte to macrophage differentiation-associated
MPZL2 myelin protein zero-like 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDGFRL platelet-derived growth factor receptor-like
PDLIM3 PDZ and LIM domain 3
RELN reelin
RGS5 regulator of G-protein signaling 5
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEPW1 selenoprotein W, 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TFPI2 tissue factor pathway inhibitor 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TUBA1A tubulin, alpha 1a