BRD-K37764012_PF-3758309_HT29_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

202 genes differentially expressed following the BRD-K37764012_PF-3758309_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADCY9 adenylate cyclase 9
AGR2 anterior gradient 2
BASP1 brain abundant, membrane attached signal protein 1
BEX4 brain expressed, X-linked 4
BIRC3 baculoviral IAP repeat containing 3
BPIFA1 BPI fold containing family A, member 1
BTG3 BTG family, member 3
C6ORF62 chromosome 6 open reading frame 62
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CCL20 chemokine (C-C motif) ligand 20
CCNG2 cyclin G2
CES1 carboxylesterase 1
CFB complement factor B
CHMP1B charged multivesicular body protein 1B
COL9A2 collagen, type IX, alpha 2
CTGF connective tissue growth factor
CTSA cathepsin A
CXCL8 chemokine (C-X-C motif) ligand 8
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DYNLRB1 dynein, light chain, roadblock-type 1
EDN1 endothelin 1
ETNK1 ethanolamine kinase 1
FBN2 fibrillin 2
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOLR1 folate receptor 1 (adult)
FOXJ3 forkhead box J3
GABARAP GABA(A) receptor-associated protein
GABARAPL2 GABA(A) receptor-associated protein-like 2
GOLM1 golgi membrane protein 1
GRN granulin
GSDMB gasdermin B
GSN gelsolin
GSTM3 glutathione S-transferase mu 3 (brain)
HIST1H1C histone cluster 1, H1c
HIST1H2BC histone cluster 1, H2bc
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HSPA1A heat shock 70kDa protein 1A
IDS iduronate 2-sulfatase
IER5 immediate early response 5
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
ITFG1 integrin alpha FG-GAP repeat containing 1
JAG1 jagged 1
JUNB jun B proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KLHL24 kelch-like family member 24
LAMA3 laminin, alpha 3
LAMC2 laminin, gamma 2
LBH limb bud and heart development
LCN2 lipocalin 2
LGALS1 lectin, galactoside-binding, soluble, 1
LRP10 low density lipoprotein receptor-related protein 10
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MEIS1 Meis homeobox 1
MIR22HG MIR22 host gene
MMP7 matrix metallopeptidase 7
MSMB microseminoprotein, beta-
MXI1 MAX interactor 1, dimerization protein
MXRA7 matrix-remodelling associated 7
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDZK1IP1 PDZK1 interacting protein 1
PI3 peptidase inhibitor 3, skin-derived
PKP2 plakophilin 2
PNKP polynucleotide kinase 3'-phosphatase
PPAP2B phosphatidic acid phosphatase type 2B
RAB9A RAB9A, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIOK3 RIO kinase 3
RNF103 ring finger protein 103
RRAD Ras-related associated with diabetes
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAND1 SCAN domain containing 1
SDC4 syndecan 4
SIDT2 SID1 transmembrane family, member 2
SMAD3 SMAD family member 3
SMAD7 SMAD family member 7
SST somatostatin
STK26 serine/threonine protein kinase 26
TGM2 transglutaminase 2
TICAM1 toll-like receptor adaptor molecule 1
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMC5 transmembrane channel-like 5
TMEM59 transmembrane protein 59
TNIP1 TNFAIP3 interacting protein 1
TPD52 tumor protein D52
TPP1 tripeptidyl peptidase I
TSPYL5 TSPY-like 5
TUBA1A tubulin, alpha 1a
VIM vimentin
WDR45 WD repeat domain 45
WDTC1 WD and tetratricopeptide repeats 1
WFDC2 WAP four-disulfide core domain 2
YPEL5 yippee-like 5 (Drosophila)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
AQP3 aquaporin 3 (Gill blood group)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
AUTS2 autism susceptibility candidate 2
BCHE butyrylcholinesterase
C1S complement component 1, s subcomponent
C20ORF27 chromosome 20 open reading frame 27
C7 complement component 7
CALB2 calbindin 2
CALR calreticulin
CCL19 chemokine (C-C motif) ligand 19
CCNA2 cyclin A2
CDK1 cyclin-dependent kinase 1
CDK4 cyclin-dependent kinase 4
CTSH cathepsin H
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL9 chemokine (C-X-C motif) ligand 9
DAPK1 death-associated protein kinase 1
DCN decorin
DHFR dihydrofolate reductase
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMTF1 cyclin D binding myb-like transcription factor 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EREG epiregulin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FKBP11 FK506 binding protein 11, 19 kDa
GGCT gamma-glutamylcyclotransferase
GINS2 GINS complex subunit 2 (Psf2 homolog)
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GRWD1 glutamate-rich WD repeat containing 1
GTPBP8 GTP-binding protein 8 (putative)
HOXC6 homeobox C6
HPRT1 hypoxanthine phosphoribosyltransferase 1
IFI16 interferon, gamma-inducible protein 16
IFITM1 interferon induced transmembrane protein 1
IFRD2 interferon-related developmental regulator 2
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IL33 interleukin 33
ITGB1BP1 integrin beta 1 binding protein 1
ITM2A integral membrane protein 2A
KRT23 keratin 23, type I
LBR lamin B receptor
LEPR leptin receptor
LTF lactotransferrin
LY6E lymphocyte antigen 6 complex, locus E
MAL mal, T-cell differentiation protein
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MRPL3 mitochondrial ribosomal protein L3
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MTA1 metastasis associated 1
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOL11 nucleolar protein 11
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRN1 neuritin 1
PCNA proliferating cell nuclear antigen
PLK1 polo-like kinase 1
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PUS7 pseudouridylate synthase 7 (putative)
PYCR1 pyrroline-5-carboxylate reductase 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBM34 RNA binding motif protein 34
RFC3 replication factor C (activator 1) 3, 38kDa
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SEPHS1 selenophosphate synthetase 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRGN serglycin
SRM spermidine synthase
SRSF3 serine/arginine-rich splicing factor 3
SRSF7 serine/arginine-rich splicing factor 7
SSRP1 structure specific recognition protein 1
STEAP3 STEAP family member 3, metalloreductase
STMN1 stathmin 1
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TMEM109 transmembrane protein 109
TMPO thymopoietin
TNC tenascin C
TOP2A topoisomerase (DNA) II alpha 170kDa
TRBC1 T cell receptor beta constant 1
TYMS thymidylate synthetase
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UNG uracil-DNA glycosylase
USP1 ubiquitin specific peptidase 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)