BRD-K37687095_AZD-8330_SKBR3_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K37687095_AZD-8330_SKBR3_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFH complement factor H
COBL cordon-bleu WH2 repeat protein
DPP4 dipeptidyl-peptidase 4
FAM57A family with sequence similarity 57, member A
FBN1 fibrillin 1
FSD1 fibronectin type III and SPRY domain containing 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HOPX HOP homeobox
KRT18 keratin 18, type I
MAOA monoamine oxidase A
MT1E metallothionein 1E
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERINC5 serine incorporator 5
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPA2 surfactant protein A2
SFTPC surfactant protein C
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SRGN serglycin
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TFPI2 tissue factor pathway inhibitor 2
TM4SF1 transmembrane 4 L six family member 1
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
CA2 carbonic anhydrase II
CD200 CD200 molecule
COL4A5 collagen, type IV, alpha 5
CREB1 cAMP responsive element binding protein 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP4 dual specificity phosphatase 4
F13A1 coagulation factor XIII, A1 polypeptide
FN1 fibronectin 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
KDM5D lysine (K)-specific demethylase 5D
KRT5 keratin 5, type II
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RPS4Y1 ribosomal protein S4, Y-linked 1
RYBP RING1 and YY1 binding protein
SMAD1 SMAD family member 1
TSPYL5 TSPY-like 5