BRD-K37687095_AZD-8330_MDAMB231_3_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-K37687095_AZD-8330_MDAMB231_3_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
AFP alpha-fetoprotein
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOA2 apolipoprotein A-II
APOE apolipoprotein E
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
BAMBI BMP and activin membrane-bound inhibitor
CDH3 cadherin 3, type 1, P-cadherin (placental)
CPB1 carboxypeptidase B1 (tissue)
CXCL12 chemokine (C-X-C motif) ligand 12
DLK1 delta-like 1 homolog (Drosophila)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ESR1 estrogen receptor 1
FBLN1 fibulin 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
HIST1H1C histone cluster 1, H1c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPB8 heat shock 22kDa protein 8
IGFBP5 insulin-like growth factor binding protein 5
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
LEF1 lymphoid enhancer-binding factor 1
MARCKSL1 MARCKS-like 1
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
MPP1 membrane protein, palmitoylated 1, 55kDa
MUC16 mucin 16, cell surface associated
PCOLCE procollagen C-endopeptidase enhancer
PEX11A peroxisomal biogenesis factor 11 alpha
RBPMS RNA binding protein with multiple splicing
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TCF4 transcription factor 4
TFPI2 tissue factor pathway inhibitor 2
TGIF1 TGFB-induced factor homeobox 1

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ADRB2 adrenoceptor beta 2, surface
ALCAM activated leukocyte cell adhesion molecule
AMIGO2 adhesion molecule with Ig-like domain 2
ARG1 arginase 1
BCHE butyrylcholinesterase
CALCA calcitonin-related polypeptide alpha
CCND1 cyclin D1
CHN1 chimerin 1
CHRDL1 chordin-like 1
CREB1 cAMP responsive element binding protein 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EPHA2 EPH receptor A2
ETV1 ets variant 1
FABP4 fatty acid binding protein 4, adipocyte
FABP7 fatty acid binding protein 7, brain
FBP1 fructose-1,6-bisphosphatase 1
FOSL1 FOS-like antigen 1
FOXC1 forkhead box C1
GLS glutaminase
GPM6B glycoprotein M6B
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IER3 immediate early response 3
KRT7 keratin 7, type II
LIF leukemia inhibitory factor
LMO4 LIM domain only 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYBPC1 myosin binding protein C, slow type
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAV3 neuron navigator 3
NRCAM neuronal cell adhesion molecule
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAC8 placenta-specific 8
PROM1 prominin 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTX3 pentraxin 3, long
RBMS1 RNA binding motif, single stranded interacting protein 1
RGCC regulator of cell cycle
RSL1D1 ribosomal L1 domain containing 1
SOWAHC sosondowah ankyrin repeat domain family member C
STX1A syntaxin 1A (brain)
SYNM synemin, intermediate filament protein
TGM2 transglutaminase 2
TNIP1 TNFAIP3 interacting protein 1
TUBB2A tubulin, beta 2A class IIa
VCAN versican
ZNF91 zinc finger protein 91