BRD-K37687095_AZD-8330_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K37687095_AZD-8330_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
GPER1 G protein-coupled estrogen receptor 1
HES1 hes family bHLH transcription factor 1
HMGN3 high mobility group nucleosomal binding domain 3
IFI6 interferon, alpha-inducible protein 6
IRF9 interferon regulatory factor 9
MARCKSL1 MARCKS-like 1
METTL7A methyltransferase like 7A
MX2 MX dynamin-like GTPase 2
NDRG1 N-myc downstream regulated 1
NPY1R neuropeptide Y receptor Y1
RPS4Y1 ribosomal protein S4, Y-linked 1
SCG5 secretogranin V
STAT1 signal transducer and activator of transcription 1, 91kDa
SYNGR3 synaptogyrin 3
TRIM38 tripartite motif containing 38

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANGPTL2 angiopoietin-like 2
ANXA1 annexin A1
BID BH3 interacting domain death agonist
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD52 CD52 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
COL11A1 collagen, type XI, alpha 1
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CXCL12 chemokine (C-X-C motif) ligand 12
EGR1 early growth response 1
EIF5A eukaryotic translation initiation factor 5A
EMP1 epithelial membrane protein 1
FAM129A family with sequence similarity 129, member A
FBXO21 F-box protein 21
FST follistatin
FZD7 frizzled class receptor 7
GPRC5A G protein-coupled receptor, class C, group 5, member A
GPX3 glutathione peroxidase 3
IFRD2 interferon-related developmental regulator 2
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ITGB5 integrin, beta 5
LOXL1 lysyl oxidase-like 1
LPL lipoprotein lipase
NBL1 neuroblastoma 1, DAN family BMP antagonist
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PMP22 peripheral myelin protein 22
PPARG peroxisome proliferator-activated receptor gamma
PXDN peroxidasin
PYGL phosphorylase, glycogen, liver
S100P S100 calcium binding protein P
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY2 sprouty homolog 2 (Drosophila)
ZDHHC6 zinc finger, DHHC-type containing 6