BRD-K37687095_AZD-8330_MCF10A_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

107 genes differentially expressed following the BRD-K37687095_AZD-8330_MCF10A_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ABHD4 abhydrolase domain containing 4
BLNK B-cell linker
CNOT4 CCR4-NOT transcription complex, subunit 4
HIST1H1C histone cluster 1, H1c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
KIF14 kinesin family member 14
MAN1A1 mannosidase, alpha, class 1A, member 1
MTSS1 metastasis suppressor 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NPR3 natriuretic peptide receptor 3
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PEX11A peroxisomal biogenesis factor 11 alpha
RGS2 regulator of G-protein signaling 2
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
STOM stomatin
TCTN1 tectonic family member 1
TGFBI transforming growth factor, beta-induced, 68kDa
TLE4 transducin-like enhancer of split 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTN1 actinin, alpha 1
AKAP12 A kinase (PRKA) anchor protein 12
AQP3 aquaporin 3 (Gill blood group)
ARL4C ADP-ribosylation factor-like 4C
CCL20 chemokine (C-C motif) ligand 20
CCND1 cyclin D1
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CNN1 calponin 1, basic, smooth muscle
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL6A3 collagen, type VI, alpha 3
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DES desmin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
EIF5 eukaryotic translation initiation factor 5
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EMP1 epithelial membrane protein 1
EPHA2 EPH receptor A2
EREG epiregulin
ETV5 ets variant 5
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOSL1 FOS-like antigen 1
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GTF3A general transcription factor IIIA
HBEGF heparin-binding EGF-like growth factor
HES1 hes family bHLH transcription factor 1
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
IER3 immediate early response 3
ITGA6 integrin, alpha 6
JAG1 jagged 1
LRRC17 leucine rich repeat containing 17
LTF lactotransferrin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMD monocyte to macrophage differentiation-associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH11 myosin, heavy chain 11, smooth muscle
MYLK myosin light chain kinase
NET1 neuroepithelial cell transforming 1
NT5E 5'-nucleotidase, ecto (CD73)
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLAT plasminogen activator, tissue
PLN phospholamban
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POSTN periostin, osteoblast specific factor
PRSS3 protease, serine, 3
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RGS4 regulator of G-protein signaling 4
SDC4 syndecan 4
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SLPI secretory leukocyte peptidase inhibitor
SNAP25 synaptosomal-associated protein, 25kDa
SOX11 SRY (sex determining region Y)-box 11
SOX9 SRY (sex determining region Y)-box 9
SPAG4 sperm associated antigen 4
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
STC1 stanniocalcin 1
STX1A syntaxin 1A (brain)
TACSTD2 tumor-associated calcium signal transducer 2
TGFA transforming growth factor, alpha
TM4SF1 transmembrane 4 L six family member 1
TSC22D1 TSC22 domain family, member 1
VEGFA vascular endothelial growth factor A
WFDC2 WAP four-disulfide core domain 2
WWTR1 WW domain containing transcription regulator 1
ZEB1 zinc finger E-box binding homeobox 1