BRD-K37687095_AZD-8330_HS578T_3_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K37687095_AZD-8330_HS578T_3_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BPHL biphenyl hydrolase-like (serine hydrolase)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COMP cartilage oligomeric matrix protein
FGFR2 fibroblast growth factor receptor 2
FOXN3 forkhead box N3
GAS1 growth arrest-specific 1
GOLGA8A golgin A8 family, member A
GREM1 gremlin 1, DAN family BMP antagonist
HDGFRP3 hepatoma-derived growth factor, related protein 3
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
IGKV1-5 immunoglobulin kappa variable 1-5
IGL immunoglobulin lambda locus
MAOB monoamine oxidase B
MAPK13 mitogen-activated protein kinase 13
MATN2 matrilin 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLXNC1 plexin C1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SESN1 sestrin 1
SOCS2 suppressor of cytokine signaling 2
STXBP2 syntaxin binding protein 2
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
ANPEP alanyl (membrane) aminopeptidase
ARHGAP29 Rho GTPase activating protein 29
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
DUSP6 dual specificity phosphatase 6
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EMP1 epithelial membrane protein 1
FOSL1 FOS-like antigen 1
FXYD5 FXYD domain containing ion transport regulator 5
GNA13 guanine nucleotide binding protein (G protein), alpha 13
HMGA2 high mobility group AT-hook 2
IFI16 interferon, gamma-inducible protein 16
IFI27 interferon, alpha-inducible protein 27
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
JUN jun proto-oncogene
LAMA3 laminin, alpha 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCL1 myeloid cell leukemia 1
MET MET proto-oncogene, receptor tyrosine kinase
MGLL monoglyceride lipase
MTERF3 mitochondrial transcription termination factor 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NRP1 neuropilin 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAUR plasminogen activator, urokinase receptor
PNMA2 paraneoplastic Ma antigen 2
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PRKCH protein kinase C, eta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
REG3A regenerating islet-derived 3 alpha
RGS5 regulator of G-protein signaling 5
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY2 sprouty homolog 2 (Drosophila)
STX1A syntaxin 1A (brain)
THBS1 thrombospondin 1
TLR4 toll-like receptor 4
TSPAN4 tetraspanin 4
ZIC1 Zic family member 1