BRD-K37687095_AZD-8330_HEPG2_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K37687095_AZD-8330_HEPG2_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCY7 adenylate cyclase 7
APOD apolipoprotein D
CCNA1 cyclin A1
CD8A CD8a molecule
CKS2 CDC28 protein kinase regulatory subunit 2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DAPK1 death-associated protein kinase 1
DENND2D DENN/MADD domain containing 2D
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP7 fatty acid binding protein 7, brain
FAM65B family with sequence similarity 65, member B
FGG fibrinogen gamma chain
FST follistatin
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GPC3 glypican 3
GPX7 glutathione peroxidase 7
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HSDL2 hydroxysteroid dehydrogenase like 2
HSPA1A heat shock 70kDa protein 1A
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ITM2A integral membrane protein 2A
KDM5D lysine (K)-specific demethylase 5D
MAGED1 melanoma antigen family D1
NOTCH1 notch 1
PROM1 prominin 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SRPX sushi-repeat containing protein, X-linked
TARP TCR gamma alternate reading frame protein

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
AQP1 aquaporin 1 (Colton blood group)
CA2 carbonic anhydrase II
CADM1 cell adhesion molecule 1
CD9 CD9 molecule
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CXCL14 chemokine (C-X-C motif) ligand 14
CYCS cytochrome c, somatic
DKK3 dickkopf WNT signaling pathway inhibitor 3
DSP desmoplakin
DUSP6 dual specificity phosphatase 6
EIF5A eukaryotic translation initiation factor 5A
GAL galanin/GMAP prepropeptide
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
IFRD2 interferon-related developmental regulator 2
KRT18 keratin 18, type I
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MMP9 matrix metallopeptidase 9
PMEPA1 prostate transmembrane protein, androgen induced 1
RNF167 ring finger protein 167
STC1 stanniocalcin 1
SULF1 sulfatase 1
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
THBS1 thrombospondin 1
TKTL1 transketolase-like 1
TNC tenascin C
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TPBG trophoblast glycoprotein
XIST X inactive specific transcript (non-protein coding)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon