BRD-K37687095_AZD-8330_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

99 genes differentially expressed following the BRD-K37687095_AZD-8330_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ACSL1 acyl-CoA synthetase long-chain family member 1
AQP1 aquaporin 1 (Colton blood group)
ARG2 arginase 2
ARID5B AT rich interactive domain 5B (MRF1-like)
ATF3 activating transcription factor 3
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BAMBI BMP and activin membrane-bound inhibitor
BPGM 2,3-bisphosphoglycerate mutase
C8ORF4 chromosome 8 open reading frame 4
CALB1 calbindin 1, 28kDa
CCL2 chemokine (C-C motif) ligand 2
CD9 CD9 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CRYAB crystallin, alpha B
CSRP2 cysteine and glycine-rich protein 2
CST1 cystatin SN
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL10 chemokine (C-X-C motif) ligand 10
DEPTOR DEP domain containing MTOR-interacting protein
DLK1 delta-like 1 homolog (Drosophila)
EDN1 endothelin 1
EFNA1 ephrin-A1
EGF epidermal growth factor
FGFR2 fibroblast growth factor receptor 2
FGG fibrinogen gamma chain
FMO3 flavin containing monooxygenase 3
FST follistatin
GAGE3 G antigen 3
GSN gelsolin
H1F0 H1 histone family, member 0
ICAM1 intercellular adhesion molecule 1
IFI27 interferon, alpha-inducible protein 27
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGHM immunoglobulin heavy constant mu
INHBA inhibin, beta A
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
KRT7 keratin 7, type II
MT1X metallothionein 1X
MTUS1 microtubule associated tumor suppressor 1
MUC1 mucin 1, cell surface associated
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEFL neurofilament, light polypeptide
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NUPR1 nuclear protein, transcriptional regulator, 1
PDE4DIP phosphodiesterase 4D interacting protein
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLSCR1 phospholipid scramblase 1
S100A2 S100 calcium binding protein A2
SC5D sterol-C5-desaturase
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SMCO4 single-pass membrane protein with coiled-coil domains 4
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
STAT1 signal transducer and activator of transcription 1, 91kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
THBS2 thrombospondin 2
TRIM29 tripartite motif containing 29
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
BEX1 brain expressed, X-linked 1
CCND1 cyclin D1
CLIC4 chloride intracellular channel 4
COL4A5 collagen, type IV, alpha 5
CPVL carboxypeptidase, vitellogenic-like
DUSP6 dual specificity phosphatase 6
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGR1 early growth response 1
FJX1 four jointed box 1 (Drosophila)
FOSL1 FOS-like antigen 1
FRZB frizzled-related protein
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
HBB hemoglobin, beta
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ITGA6 integrin, alpha 6
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAPK13 mitogen-activated protein kinase 13
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NT5E 5'-nucleotidase, ecto (CD73)
PHLDA1 pleckstrin homology-like domain, family A, member 1
REEP1 receptor accessory protein 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SRSF7 serine/arginine-rich splicing factor 7
STK10 serine/threonine kinase 10
STX1A syntaxin 1A (brain)
TBX2 T-box 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TSPAN4 tetraspanin 4
WT1 Wilms tumor 1
XIST X inactive specific transcript (non-protein coding)