BRD-K37687095_AZD-8330_HA1E_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K37687095_AZD-8330_HA1E_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARID5B AT rich interactive domain 5B (MRF1-like)
AUTS2 autism susceptibility candidate 2
BIRC3 baculoviral IAP repeat containing 3
C6ORF62 chromosome 6 open reading frame 62
CADM1 cell adhesion molecule 1
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFLAR CASP8 and FADD-like apoptosis regulator
CKB creatine kinase, brain
CSRP2 cysteine and glycine-rich protein 2
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
DAAM1 dishevelled associated activator of morphogenesis 1
DDIT4 DNA-damage-inducible transcript 4
DEPTOR DEP domain containing MTOR-interacting protein
DMD dystrophin
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EGF epidermal growth factor
EGLN3 egl-9 family hypoxia-inducible factor 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EXPH5 exophilin 5
FAM129A family with sequence similarity 129, member A
FGFR2 fibroblast growth factor receptor 2
FILIP1L filamin A interacting protein 1-like
GBP1 guanylate binding protein 1, interferon-inducible
GSN gelsolin
ICAM1 intercellular adhesion molecule 1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IGFBP5 insulin-like growth factor binding protein 5
IL32 interleukin 32
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IRF9 interferon regulatory factor 9
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KLF9 Kruppel-like factor 9
LDLR low density lipoprotein receptor
LGALS3 lectin, galactoside-binding, soluble, 3
MGP matrix Gla protein
MPPED2 metallophosphoesterase domain containing 2
MX1 MX dynamin-like GTPase 1
NAV2 neuron navigator 2
NDRG2 NDRG family member 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
PALLD palladin, cytoskeletal associated protein
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLSCR1 phospholipid scramblase 1
PPAP2A phosphatidic acid phosphatase type 2A
RCAN1 regulator of calcineurin 1
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC39A4 solute carrier family 39 (zinc transporter), member 4
STAT1 signal transducer and activator of transcription 1, 91kDa
SULF1 sulfatase 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TPD52L1 tumor protein D52-like 1
TSC22D3 TSC22 domain family, member 3
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARHGAP29 Rho GTPase activating protein 29
BICC1 BicC family RNA binding protein 1
C2CD5 C2 calcium-dependent domain containing 5
CCND1 cyclin D1
CD24 CD24 molecule
DUSP2 dual specificity phosphatase 2
EFHD2 EF-hand domain family, member D2
EGR1 early growth response 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EVI2B ecotropic viral integration site 2B
FOSL1 FOS-like antigen 1
GLRX glutaredoxin (thioltransferase)
GPX1 glutathione peroxidase 1
H3F3B H3 histone, family 3B (H3.3B)
HMGA1 high mobility group AT-hook 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPH1 heat shock 105kDa/110kDa protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ITGB5 integrin, beta 5
MTCL1 microtubule crosslinking factor 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PLK2 polo-like kinase 2
PPARG peroxisome proliferator-activated receptor gamma
RAI14 retinoic acid induced 14
SFRP1 secreted frizzled-related protein 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
STX1A syntaxin 1A (brain)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM4SF1 transmembrane 4 L six family member 1
VCAN versican