BRD-K37687095_AZD-8330_BT20_3_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K37687095_AZD-8330_BT20_3_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
BAMBI BMP and activin membrane-bound inhibitor
BASP1 brain abundant, membrane attached signal protein 1
C3 complement component 3
CP ceruloplasmin (ferroxidase)
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
DUSP10 dual specificity phosphatase 10
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
HSPA1A heat shock 70kDa protein 1A
IGL immunoglobulin lambda locus
LCN2 lipocalin 2
LTF lactotransferrin
MMP7 matrix metallopeptidase 7
NR2F2 nuclear receptor subfamily 2, group F, member 2
OLFM1 olfactomedin 1
PDZK1IP1 PDZK1 interacting protein 1
PTCH1 patched 1
RAB15 RAB15, member RAS oncogene family
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
S100A9 S100 calcium binding protein A9
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLPI secretory leukocyte peptidase inhibitor
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VTCN1 V-set domain containing T cell activation inhibitor 1
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AREG amphiregulin
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
BMP2 bone morphogenetic protein 2
CA2 carbonic anhydrase II
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
EGR2 early growth response 2
EREG epiregulin
ERGIC3 ERGIC and golgi 3
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
GDF15 growth differentiation factor 15
GEM GTP binding protein overexpressed in skeletal muscle
HBEGF heparin-binding EGF-like growth factor
IER3 immediate early response 3
LIF leukemia inhibitory factor
LOX lysyl oxidase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MYC v-myc avian myelocytomatosis viral oncogene homolog
NRGN neurogranin (protein kinase C substrate, RC3)
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
SDC4 syndecan 4
SPP1 secreted phosphoprotein 1