BRD-K37687095_AZD-8330_BT20_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-K37687095_AZD-8330_BT20_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
BAMBI BMP and activin membrane-bound inhibitor
BCL6 B-cell CLL/lymphoma 6
BIK BCL2-interacting killer (apoptosis-inducing)
CD14 CD14 molecule
CFB complement factor B
EFNA1 ephrin-A1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EMX2 empty spiracles homeobox 2
FKBP11 FK506 binding protein 11, 19 kDa
GLUL glutamate-ammonia ligase
HIST1H2AC histone cluster 1, H2ac
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
LCN2 lipocalin 2
MUC1 mucin 1, cell surface associated
MYRF myelin regulatory factor
NPIPB3 nuclear pore complex interacting protein family, member B3
PDZK1IP1 PDZK1 interacting protein 1
PI3 peptidase inhibitor 3, skin-derived
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PRKCD protein kinase C, delta
PRUNE2 prune homolog 2 (Drosophila)
STK26 serine/threonine protein kinase 26
TNS1 tensin 1
TSC22D3 TSC22 domain family, member 3
TWF2 twinfilin actin binding protein 2
XBP1 X-box binding protein 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRF5 adhesion G protein-coupled receptor F5
AREG amphiregulin
CCND1 cyclin D1
CDC45 cell division cycle 45
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
DPYSL2 dihydropyrimidinase-like 2
DUSP4 dual specificity phosphatase 4
EGR2 early growth response 2
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
IER3 immediate early response 3
IGF1 insulin-like growth factor 1 (somatomedin C)
ITGB5 integrin, beta 5
MFSD10 major facilitator superfamily domain containing 10
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SOWAHC sosondowah ankyrin repeat domain family member C
THBS1 thrombospondin 1
TSPAN4 tetraspanin 4
TSPAN6 tetraspanin 6