BRD-K37687095_AZD-8330_BT20_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K37687095_AZD-8330_BT20_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
BTG2 BTG family, member 2
CD177 CD177 molecule
CLDN3 claudin 3
CLU clusterin
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL14 chemokine (C-X-C motif) ligand 14
DHCR24 24-dehydrocholesterol reductase
FCGBP Fc fragment of IgG binding protein
FKBP11 FK506 binding protein 11, 19 kDa
GCH1 GTP cyclohydrolase 1
GJA1 gap junction protein, alpha 1, 43kDa
HBB hemoglobin, beta
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
IL32 interleukin 32
KDM5B lysine (K)-specific demethylase 5B
KRT19 keratin 19, type I
KRT4 keratin 4, type II
LCN2 lipocalin 2
MOXD1 monooxygenase, DBH-like 1
MUC2 mucin 2, oligomeric mucus/gel-forming
MVP major vault protein
NDRG1 N-myc downstream regulated 1
PRKCD protein kinase C, delta
RAB31 RAB31, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RGS1 regulator of G-protein signaling 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SOX2 SRY (sex determining region Y)-box 2
SRGN serglycin
TFPI2 tissue factor pathway inhibitor 2
THAP11 THAP domain containing 11
TRIM22 tripartite motif containing 22
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ARL4C ADP-ribosylation factor-like 4C
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
DCN decorin
EIF5A eukaryotic translation initiation factor 5A
EREG epiregulin
ETV5 ets variant 5
FOSL1 FOS-like antigen 1
IPO5 importin 5
ITGB5 integrin, beta 5
SEPT11 septin 11
SLC43A3 solute carrier family 43, member 3
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY2 sprouty homolog 2 (Drosophila)
TIMP1 TIMP metallopeptidase inhibitor 1
TM4SF1 transmembrane 4 L six family member 1
TRAPPC3 trafficking protein particle complex 3
TRIP6 thyroid hormone receptor interactor 6
TUBB2A tubulin, beta 2A class IIa
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28