BRD-K37393297_1-(3,4-Dihydroxy-phenyl)-2-(4,6-dimethyl-pyrimidin-2-ylsulfanyl)-ethanone_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K37393297_1-(3,4-Dihydroxy-phenyl)-2-(4,6-dimethyl-pyrimidin-2-ylsulfanyl)-ethanone_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYTL1 cytokine-like 1
EIF5A eukaryotic translation initiation factor 5A
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FOLR1 folate receptor 1 (adult)
KCTD12 potassium channel tetramerization domain containing 12
PENK proenkephalin
PLK1 polo-like kinase 1
PNMA2 paraneoplastic Ma antigen 2
RPS5 ribosomal protein S5
RUNX3 runt-related transcription factor 3
SV2C synaptic vesicle glycoprotein 2C
TNPO1 transportin 1
TSPAN13 tetraspanin 13
TSPAN3 tetraspanin 3
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARL4C ADP-ribosylation factor-like 4C
AZGP1 alpha-2-glycoprotein 1, zinc-binding
FABP4 fatty acid binding protein 4, adipocyte
FGFR2 fibroblast growth factor receptor 2
GCLC glutamate-cysteine ligase, catalytic subunit
GLRX glutaredoxin (thioltransferase)
GPRC5B G protein-coupled receptor, class C, group 5, member B
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IFI16 interferon, gamma-inducible protein 16
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KDR kinase insert domain receptor
KLK8 kallikrein-related peptidase 8
KRT15 keratin 15, type I
KRT23 keratin 23, type I
LPAR6 lysophosphatidic acid receptor 6
MDFIC MyoD family inhibitor domain containing
MME membrane metallo-endopeptidase
MYOF myoferlin
POLR1D polymerase (RNA) I polypeptide D, 16kDa
PPAP2B phosphatidic acid phosphatase type 2B
PSAP prosaposin
RGCC regulator of cell cycle
SFRP1 secreted frizzled-related protein 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SNX10 sorting nexin 10
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TM9SF3 transmembrane 9 superfamily member 3
TMSB15A thymosin beta 15a