BRD-K37372998_6-amino-1-benzyl-3-methyl-5-nitroso-2-thioxo-2,3-dihydropyrimidin-4(1H)-one KAJ-8_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K37372998_6-amino-1-benzyl-3-methyl-5-nitroso-2-thioxo-2,3-dihydropyrimidin-4(1H)-one KAJ-8_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AURKB aurora kinase B
CD300A CD300a molecule
CD93 CD93 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC2B C-type lectin domain family 2, member B
CORO1A coronin, actin binding protein, 1A
CP ceruloplasmin (ferroxidase)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
ICAM2 intercellular adhesion molecule 2
KDM5D lysine (K)-specific demethylase 5D
LRRC15 leucine rich repeat containing 15
MCM5 minichromosome maintenance complex component 5
PECAM1 platelet/endothelial cell adhesion molecule 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POSTN periostin, osteoblast specific factor
PRKX protein kinase, X-linked
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGS1 regulator of G-protein signaling 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
TGFB3 transforming growth factor, beta 3

decreased expression

Symbol Name
ANKRD12 ankyrin repeat domain 12
AQP3 aquaporin 3 (Gill blood group)
BASP1 brain abundant, membrane attached signal protein 1
BCL6 B-cell CLL/lymphoma 6
CFD complement factor D (adipsin)
CST3 cystatin C
CSTA cystatin A (stefin A)
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GCLC glutamate-cysteine ligase, catalytic subunit
GOLGA8A golgin A8 family, member A
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IRS2 insulin receptor substrate 2
KYNU kynureninase
LITAF lipopolysaccharide-induced TNF factor
METTL7A methyltransferase like 7A
PGAP3 post-GPI attachment to proteins 3
RAB31 RAB31, member RAS oncogene family
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UGDH UDP-glucose 6-dehydrogenase
WNT5A wingless-type MMTV integration site family, member 5A