BRD-K37340241_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

94 genes differentially expressed following the BRD-K37340241_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADRB2 adrenoceptor beta 2, surface
AFF1 AF4/FMR2 family, member 1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
CD164 CD164 molecule, sialomucin
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CELF2 CUGBP, Elav-like family member 2
CENPU centromere protein U
CKS2 CDC28 protein kinase regulatory subunit 2
CRYZ crystallin, zeta (quinone reductase)
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DUSP10 dual specificity phosphatase 10
FXYD3 FXYD domain containing ion transport regulator 3
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GLO1 glyoxalase I
GNG10 guanine nucleotide binding protein (G protein), gamma 10
IFI27 interferon, alpha-inducible protein 27
IGFBP7 insulin-like growth factor binding protein 7
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITM2A integral membrane protein 2A
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MAP7 microtubule-associated protein 7
MYO6 myosin VI
NID2 nidogen 2 (osteonidogen)
NRIP1 nuclear receptor interacting protein 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLXNC1 plexin C1
PNISR PNN-interacting serine/arginine-rich protein
PRAME preferentially expressed antigen in melanoma
PRKCB protein kinase C, beta
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
SELL selectin L
SERINC5 serine incorporator 5
SMS spermine synthase
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK26 serine/threonine protein kinase 26
TARBP1 TAR (HIV-1) RNA binding protein 1
TMEM176A transmembrane protein 176A
TOP2A topoisomerase (DNA) II alpha 170kDa
TSPAN8 tetraspanin 8
UBE2A ubiquitin-conjugating enzyme E2A
UFL1 UFM1-specific ligase 1
URI1 URI1, prefoldin-like chaperone
VIM vimentin
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADRM1 adhesion regulating molecule 1
AKAP12 A kinase (PRKA) anchor protein 12
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
B3GNT1
BCL6 B-cell CLL/lymphoma 6
BSG basigin (Ok blood group)
C6ORF62 chromosome 6 open reading frame 62
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CRIP2 cysteine-rich protein 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRYAB crystallin, alpha B
CTSD cathepsin D
CXCL8 chemokine (C-X-C motif) ligand 8
DCAF10 DDB1 and CUL4 associated factor 10
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EPN2 epsin 2
FABP7 fatty acid binding protein 7, brain
FASN fatty acid synthase
FCGBP Fc fragment of IgG binding protein
FHL1 four and a half LIM domains 1
FOSL1 FOS-like antigen 1
IGHM immunoglobulin heavy constant mu
JMJD6 jumonji domain containing 6
LOX lysyl oxidase
MT1E metallothionein 1E
MT1F metallothionein 1F
MXRA7 matrix-remodelling associated 7
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NDRG1 N-myc downstream regulated 1
NEBL nebulette
NXN nucleoredoxin
PLIN3 perilipin 3
PLK1 polo-like kinase 1
POU2AF1 POU class 2 associating factor 1
RPL37A ribosomal protein L37a
SDC2 syndecan 2
SLC38A1 solute carrier family 38, member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SRPX sushi-repeat containing protein, X-linked
TGFB1 transforming growth factor, beta 1
TGOLN2 trans-golgi network protein 2
THBS1 thrombospondin 1
TNNC1 troponin C type 1 (slow)
TPM4 tropomyosin 4