BRD-K36772364_8-{[2-oxo-2-(1-pyrrolidinyl)ethyl]thio}quinoline_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K36772364_8-{[2-oxo-2-(1-pyrrolidinyl)ethyl]thio}quinoline_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
CADM1 cell adhesion molecule 1
COL9A3 collagen, type IX, alpha 3
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FHL2 four and a half LIM domains 2
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GPM6B glycoprotein M6B
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
MAOB monoamine oxidase B
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NRCAM neuronal cell adhesion molecule
PEG3 paternally expressed 3
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
RPS4Y1 ribosomal protein S4, Y-linked 1
SCRG1 stimulator of chondrogenesis 1
SELE selectin E
SQSTM1 sequestosome 1
TF transferrin
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
BASP1 brain abundant, membrane attached signal protein 1
C8ORF4 chromosome 8 open reading frame 4
CDC25B cell division cycle 25B
CXCL10 chemokine (C-X-C motif) ligand 10
GREM1 gremlin 1, DAN family BMP antagonist
HOXA10 homeobox A10
LUM lumican
PRSS3 protease, serine, 3
RFTN1 raftlin, lipid raft linker 1
RGS2 regulator of G-protein signaling 2
TARP TCR gamma alternate reading frame protein
TSPAN8 tetraspanin 8