BRD-K36740062_GSK-1070916_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K36740062_GSK-1070916_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
AREG amphiregulin
BCL2A1 BCL2-related protein A1
BTG3 BTG family, member 3
CA2 carbonic anhydrase II
CD24 CD24 molecule
COL4A2 collagen, type IV, alpha 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
ENO1 enolase 1, (alpha)
FBXO11 F-box protein 11
GRN granulin
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KRT8 keratin 8, type II
LMCD1 LIM and cysteine-rich domains 1
MAMLD1 mastermind-like domain containing 1
MT1M metallothionein 1M
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NOV nephroblastoma overexpressed
NPR3 natriuretic peptide receptor 3
OXTR oxytocin receptor
PELO pelota homolog (Drosophila)
PKM pyruvate kinase, muscle
PRAME preferentially expressed antigen in melanoma
PSAP prosaposin
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RTN2 reticulon 2
SCYL3 SCY1-like 3 (S. cerevisiae)
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ASPH aspartate beta-hydroxylase
AUTS2 autism susceptibility candidate 2
BCL2 B-cell CLL/lymphoma 2
C3 complement component 3
COL1A2 collagen, type I, alpha 2
CPVL carboxypeptidase, vitellogenic-like
CTSH cathepsin H
CX3CR1 chemokine (C-X3-C motif) receptor 1
F3 coagulation factor III (thromboplastin, tissue factor)
FABP4 fatty acid binding protein 4, adipocyte
FGG fibrinogen gamma chain
G0S2 G0/G1 switch 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HACD2 3-hydroxyacyl-CoA dehydratase 2
HOPX HOP homeobox
HP haptoglobin
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGLL1 immunoglobulin lambda-like polypeptide 1
LMO3 LIM domain only 3 (rhombotin-like 2)
PIH1D1 PIH1 domain containing 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS4 regulator of G-protein signaling 4
SLPI secretory leukocyte peptidase inhibitor
TACC2 transforming, acidic coiled-coil containing protein 2
TCF4 transcription factor 4
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TRIB2 tribbles pseudokinase 2
TSPAN5 tetraspanin 5