BRD-K36740062_GSK-1070916_MCF7_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K36740062_GSK-1070916_MCF7_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD8A CD8a molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLTB clathrin, light chain B
COL4A5 collagen, type IV, alpha 5
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
GATA6 GATA binding protein 6
GDF15 growth differentiation factor 15
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MLPH melanophilin
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PLK2 polo-like kinase 2
PRKCH protein kinase C, eta
RGS5 regulator of G-protein signaling 5
RND3 Rho family GTPase 3
S100A14 S100 calcium binding protein A14
S100A7 S100 calcium binding protein A7
SH2D1A SH2 domain containing 1A
SPAG4 sperm associated antigen 4
TCEAL4 transcription elongation factor A (SII)-like 4
TRBC1 T cell receptor beta constant 1
TRIM22 tripartite motif containing 22
VIM vimentin
VLDLR very low density lipoprotein receptor
YPEL5 yippee-like 5 (Drosophila)
ZMAT3 zinc finger, matrin-type 3
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
CDC20 cell division cycle 20
COL1A1 collagen, type I, alpha 1
GRWD1 glutamate-rich WD repeat containing 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HMGB2 high mobility group box 2
HPRT1 hypoxanthine phosphoribosyltransferase 1
IL17RB interleukin 17 receptor B
KIF14 kinesin family member 14
MMP9 matrix metallopeptidase 9
MPPED2 metallophosphoesterase domain containing 2
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
PLK1 polo-like kinase 1
POSTN periostin, osteoblast specific factor
TF transferrin
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
UBE2C ubiquitin-conjugating enzyme E2C
VCAN versican