BRD-K36740062_GSK-1070916_MCF7_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K36740062_GSK-1070916_MCF7_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA4 annexin A4
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT4 DNA-damage-inducible transcript 4
DUOX2 dual oxidase 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FGFR3 fibroblast growth factor receptor 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXF1 forkhead box F1
GADD45A growth arrest and DNA-damage-inducible, alpha
GBP2 guanylate binding protein 2, interferon-inducible
GDF15 growth differentiation factor 15
GJA1 gap junction protein, alpha 1, 43kDa
GSN gelsolin
HBD hemoglobin, delta
HK2 hexokinase 2
KRT13 keratin 13, type I
LCN2 lipocalin 2
LRRC17 leucine rich repeat containing 17
LY6D lymphocyte antigen 6 complex, locus D
MPZL2 myelin protein zero-like 2
MTCL1 microtubule crosslinking factor 1
NID1 nidogen 1
NPTX2 neuronal pentraxin II
NR4A2 nuclear receptor subfamily 4, group A, member 2
PDGFD platelet derived growth factor D
PDZK1IP1 PDZK1 interacting protein 1
PLK2 polo-like kinase 2
PPL periplakin
QPCT glutaminyl-peptide cyclotransferase
RGS1 regulator of G-protein signaling 1
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
SCD5 stearoyl-CoA desaturase 5
SERINC5 serine incorporator 5
SGK1 serum/glucocorticoid regulated kinase 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMAD3 SMAD family member 3
STC1 stanniocalcin 1
STC2 stanniocalcin 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)

decreased expression

Symbol Name
CDC20 cell division cycle 20
EBP emopamil binding protein (sterol isomerase)
ESR1 estrogen receptor 1
GAS1 growth arrest-specific 1
HIST1H4C histone cluster 1, H4c
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KIF14 kinesin family member 14
MKI67 marker of proliferation Ki-67
PBK PDZ binding kinase
PDLIM1 PDZ and LIM domain 1
PDPN podoplanin
PLK1 polo-like kinase 1
PSD3 pleckstrin and Sec7 domain containing 3
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RPS11 ribosomal protein S11
STMN1 stathmin 1
TMPO thymopoietin
TREM1 triggering receptor expressed on myeloid cells 1
TSPAN13 tetraspanin 13
ZCCHC2 zinc finger, CCHC domain containing 2