BRD-K36740062_GSK-1070916_HT29_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K36740062_GSK-1070916_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARL4C ADP-ribosylation factor-like 4C
BZW2 basic leucine zipper and W2 domains 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EZR ezrin
FGFR3 fibroblast growth factor receptor 3
GAGE3 G antigen 3
GAS6 growth arrest-specific 6
GDF15 growth differentiation factor 15
GLRX glutaredoxin (thioltransferase)
GOLM1 golgi membrane protein 1
MECOM MDS1 and EVI1 complex locus
MMP12 matrix metallopeptidase 12
MVP major vault protein
MYOF myoferlin
NEU1 sialidase 1 (lysosomal sialidase)
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PALLD palladin, cytoskeletal associated protein
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PEG10 paternally expressed 10
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
REG3A regenerating islet-derived 3 alpha
S100A2 S100 calcium binding protein A2
SPINK1 serine peptidase inhibitor, Kazal type 1
SPON2 spondin 2, extracellular matrix protein
SQSTM1 sequestosome 1
SST somatostatin
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TACC2 transforming, acidic coiled-coil containing protein 2
TAOK3 TAO kinase 3
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TKTL1 transketolase-like 1
TRIM2 tripartite motif containing 2
TRIM8 tripartite motif containing 8
TUBA1A tubulin, alpha 1a
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
APP amyloid beta (A4) precursor protein
C7 complement component 7
CCNE2 cyclin E2
CD36 CD36 molecule (thrombospondin receptor)
CDC42 cell division cycle 42
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CXCL12 chemokine (C-X-C motif) ligand 12
DPYSL3 dihydropyrimidinase-like 3
FHL1 four and a half LIM domains 1
FLRT2 fibronectin leucine rich transmembrane protein 2
IFRD2 interferon-related developmental regulator 2
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LTF lactotransferrin
NELL2 NEL-like 2 (chicken)
NRN1 neuritin 1
PDIA3 protein disulfide isomerase family A, member 3
PDLIM1 PDZ and LIM domain 1
PEX11A peroxisomal biogenesis factor 11 alpha
PXMP2 peroxisomal membrane protein 2, 22kDa
RGS2 regulator of G-protein signaling 2
S100A12 S100 calcium binding protein A12
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SEPW1 selenoprotein W, 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
TNFAIP6 tumor necrosis factor, alpha-induced protein 6