BRD-K36740062_GSK-1070916_HA1E_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K36740062_GSK-1070916_HA1E_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ADCY9 adenylate cyclase 9
CASP10 caspase 10, apoptosis-related cysteine peptidase
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLEC2B C-type lectin domain family 2, member B
DRAM1 DNA-damage regulated autophagy modulator 1
ECM1 extracellular matrix protein 1
FABP4 fatty acid binding protein 4, adipocyte
FBLN5 fibulin 5
FHL1 four and a half LIM domains 1
FST follistatin
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BH histone cluster 1, H2bh
HIST1H2BK histone cluster 1, H2bk
HOXA5 homeobox A5
KRT15 keratin 15, type I
KRT23 keratin 23, type I
LAPTM4B lysosomal protein transmembrane 4 beta
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MEF2C myocyte enhancer factor 2C
PERP PERP, TP53 apoptosis effector
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPRO protein tyrosine phosphatase, receptor type, O
S100A12 S100 calcium binding protein A12
S100A9 S100 calcium binding protein A9
TGFBR3 transforming growth factor, beta receptor III
VNN1 vanin 1
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
ANXA3 annexin A3
BACE2 beta-site APP-cleaving enzyme 2
BIRC3 baculoviral IAP repeat containing 3
CCL2 chemokine (C-C motif) ligand 2
CD81 CD81 molecule
COCH cochlin
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
CYTH1 cytohesin 1
EGR2 early growth response 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
IL2RG interleukin 2 receptor, gamma
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MSMB microseminoprotein, beta-
MUC5B mucin 5B, oligomeric mucus/gel-forming
NEFL neurofilament, light polypeptide
NSDHL NAD(P) dependent steroid dehydrogenase-like
PTGDS prostaglandin D2 synthase 21kDa (brain)
S100P S100 calcium binding protein P
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TOX3 TOX high mobility group box family member 3
TRIB2 tribbles pseudokinase 2
TSPAN8 tetraspanin 8
ZBTB18 zinc finger and BTB domain containing 18
ZNF185 zinc finger protein 185 (LIM domain)