BRD-K36740062_GSK-1070916_A549_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-K36740062_GSK-1070916_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AREG amphiregulin
BAX BCL2-associated X protein
CA1 carbonic anhydrase I
CD44 CD44 molecule (Indian blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
EIF1 eukaryotic translation initiation factor 1
FAS Fas cell surface death receptor
FBN2 fibrillin 2
GAA glucosidase, alpha; acid
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLC glutamate-cysteine ligase, catalytic subunit
HACD1 3-hydroxyacyl-CoA dehydratase 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
LDOC1 leucine zipper, down-regulated in cancer 1
OPTN optineurin
PTPRO protein tyrosine phosphatase, receptor type, O
SESN1 sestrin 1
SFRP1 secreted frizzled-related protein 1
TP53I3 tumor protein p53 inducible protein 3
TRIM22 tripartite motif containing 22

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
CDC25A cell division cycle 25A
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CENPN centromere protein N
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CXCL14 chemokine (C-X-C motif) ligand 14
DCN decorin
EPCAM epithelial cell adhesion molecule
FAM129A family with sequence similarity 129, member A
FKBP14 FK506 binding protein 14, 22 kDa
HOXC6 homeobox C6
IGFBP5 insulin-like growth factor binding protein 5
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MARCKSL1 MARCKS-like 1
NPY1R neuropeptide Y receptor Y1
S100P S100 calcium binding protein P
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
STAR steroidogenic acute regulatory protein
STEAP1 six transmembrane epithelial antigen of the prostate 1
TSPAN8 tetraspanin 8