BRD-K36740062_GSK-1070916_A375_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K36740062_GSK-1070916_A375_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
AHNAK2 AHNAK nucleoprotein 2
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
ATF3 activating transcription factor 3
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BTG2 BTG family, member 2
C8ORF4 chromosome 8 open reading frame 4
CCNG2 cyclin G2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHN1 chimerin 1
CLCA4 chloride channel accessory 4
CRELD2 cysteine-rich with EGF-like domains 2
CRISP3 cysteine-rich secretory protein 3
DACH1 dachshund family transcription factor 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP5 dual specificity phosphatase 5
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
FABP4 fatty acid binding protein 4, adipocyte
FAM46A family with sequence similarity 46, member A
FAS Fas cell surface death receptor
FDXR ferredoxin reductase
FGFR3 fibroblast growth factor receptor 3
G0S2 G0/G1 switch 2
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GREM1 gremlin 1, DAN family BMP antagonist
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
IGF1R insulin-like growth factor 1 receptor
IGFBP5 insulin-like growth factor binding protein 5
KLF5 Kruppel-like factor 5 (intestinal)
LXN latexin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAL mal, T-cell differentiation protein
MAP7 microtubule-associated protein 7
MME membrane metallo-endopeptidase
MMP12 matrix metallopeptidase 12
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEBL nebulette
NRIP3 nuclear receptor interacting protein 3
NUPR1 nuclear protein, transcriptional regulator, 1
PCDH9 protocadherin 9
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RND3 Rho family GTPase 3
RPS27L ribosomal protein S27-like
S100A2 S100 calcium binding protein A2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SESN1 sestrin 1
SIK1 salt-inducible kinase 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SQRDL sulfide quinone reductase-like (yeast)
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TBX3 T-box 3
TCF4 transcription factor 4
TP53I3 tumor protein p53 inducible protein 3
TRIM22 tripartite motif containing 22
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
BST2 bone marrow stromal cell antigen 2
CADM1 cell adhesion molecule 1
CCL20 chemokine (C-C motif) ligand 20
CDC25A cell division cycle 25A
CRABP1 cellular retinoic acid binding protein 1
CSRP1 cysteine and glycine-rich protein 1
DSTN destrin (actin depolymerizing factor)
FAM69A family with sequence similarity 69, member A
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGL immunoglobulin lambda locus
IGLV2-23 immunoglobulin lambda variable 2-23
IL32 interleukin 32
KCTD12 potassium channel tetramerization domain containing 12
KRT18 keratin 18, type I
MELK maternal embryonic leucine zipper kinase
ODC1 ornithine decarboxylase 1
PALLD palladin, cytoskeletal associated protein
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRDX2 peroxiredoxin 2
RRM2 ribonucleotide reductase M2
SHCBP1 SHC SH2-domain binding protein 1
TM9SF3 transmembrane 9 superfamily member 3
TRIB3 tribbles pseudokinase 3