BRD-K36737713_AG 957_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-K36737713_AG 957_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ADM adrenomedullin
AHCYL2 adenosylhomocysteinase-like 2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDOA aldolase A, fructose-bisphosphate
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
BAALC brain and acute leukemia, cytoplasmic
BTG1 B-cell translocation gene 1, anti-proliferative
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
COMP cartilage oligomeric matrix protein
CTSD cathepsin D
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DSP desmoplakin
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FAM46A family with sequence similarity 46, member A
FNDC3B fibronectin type III domain containing 3B
FOXO3 forkhead box O3
FOXO4 forkhead box O4
GLA galactosidase, alpha
GPX7 glutathione peroxidase 7
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IGFBP6 insulin-like growth factor binding protein 6
ISG20 interferon stimulated exonuclease gene 20kDa
MALL mal, T-cell differentiation protein-like
MCL1 myeloid cell leukemia 1
MIR22HG MIR22 host gene
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MSX1 msh homeobox 1
MT1M metallothionein 1M
NQO1 NAD(P)H dehydrogenase, quinone 1
PIR pirin (iron-binding nuclear protein)
PLIN2 perilipin 2
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PROM1 prominin 1
PRTN3 proteinase 3
RIT1 Ras-like without CAAX 1
RTN4 reticulon 4
SCGB2A2 secretoglobin, family 2A, member 2
SQSTM1 sequestosome 1
TMEM2 transmembrane protein 2
TWF2 twinfilin actin binding protein 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGDH UDP-glucose 6-dehydrogenase
WSB1 WD repeat and SOCS box containing 1

decreased expression

Symbol Name
AHCY adenosylhomocysteinase
AKAP1 A kinase (PRKA) anchor protein 1
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
C3 complement component 3
CCL20 chemokine (C-C motif) ligand 20
CTPS1 CTP synthase 1
CXCL9 chemokine (C-X-C motif) ligand 9
DES desmin
DLK1 delta-like 1 homolog (Drosophila)
DUT deoxyuridine triphosphatase
EBP emopamil binding protein (sterol isomerase)
EIF5A eukaryotic translation initiation factor 5A
FABP6 fatty acid binding protein 6, ileal
FAM60A family with sequence similarity 60, member A
FBL fibrillarin
FJX1 four jointed box 1 (Drosophila)
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HIST3H2A histone cluster 3, H2a
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
KCTD12 potassium channel tetramerization domain containing 12
LDHB lactate dehydrogenase B
LDLR low density lipoprotein receptor
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MCAM melanoma cell adhesion molecule
MCM2 minichromosome maintenance complex component 2
MOAP1 modulator of apoptosis 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAP1L1 nucleosome assembly protein 1-like 1
NCAPD3 non-SMC condensin II complex, subunit D3
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPY neuropeptide Y
NT5DC2 5'-nucleotidase domain containing 2
PLA1A phospholipase A1 member A
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RGS10 regulator of G-protein signaling 10
RGS5 regulator of G-protein signaling 5
RPIA ribose 5-phosphate isomerase A
RPL22 ribosomal protein L22
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RUVBL1 RuvB-like AAA ATPase 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SORD sorbitol dehydrogenase
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRSF7 serine/arginine-rich splicing factor 7
ST7 suppression of tumorigenicity 7
TARBP1 TAR (HIV-1) RNA binding protein 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFAM transcription factor A, mitochondrial
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
VIM vimentin
ZFAND1 zinc finger, AN1-type domain 1