BRD-K36737713_AG 957_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K36737713_AG 957_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ATF3 activating transcription factor 3
BLVRB biliverdin reductase B
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
G6PD glucose-6-phosphate dehydrogenase
GABARAPL1 GABA(A) receptor-associated protein like 1
GAL galanin/GMAP prepropeptide
GAREM GRB2 associated, regulator of MAPK1
GPM6B glycoprotein M6B
HIST1H2AC histone cluster 1, H2ac
HIST1H2BK histone cluster 1, H2bk
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGHM immunoglobulin heavy constant mu
KCNK1 potassium channel, two pore domain subfamily K, member 1
KIF14 kinesin family member 14
LEF1 lymphoid enhancer-binding factor 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NDNF neuron-derived neurotrophic factor
NPC1 Niemann-Pick disease, type C1
PDGFA platelet-derived growth factor alpha polypeptide
PIR pirin (iron-binding nuclear protein)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RTN1 reticulon 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SRGN serglycin
TP53BP2 tumor protein p53 binding protein 2
TRIB3 tribbles pseudokinase 3
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
WSB1 WD repeat and SOCS box containing 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
CCDC85B coiled-coil domain containing 85B
CCNB2 cyclin B2
CDCA4 cell division cycle associated 4
CDK1 cyclin-dependent kinase 1
COL1A2 collagen, type I, alpha 2
ESR1 estrogen receptor 1
HADH hydroxyacyl-CoA dehydrogenase
HIST1H4C histone cluster 1, H4c
KIAA0101 KIAA0101
LAMA3 laminin, alpha 3
LIPA lipase A, lysosomal acid, cholesterol esterase
LOXL1 lysyl oxidase-like 1
MLPH melanophilin
NFIB nuclear factor I/B
PROSC proline synthetase co-transcribed homolog (bacterial)
RFC2 replication factor C (activator 1) 2, 40kDa
RGS2 regulator of G-protein signaling 2
RPA3 replication protein A3, 14kDa
RRM2 ribonucleotide reductase M2
SDC4 syndecan 4
SPDEF SAM pointed domain containing ETS transcription factor
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit
SULF1 sulfatase 1