BRD-K36737713_AG 957_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

116 genes differentially expressed following the BRD-K36737713_AG 957_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABHD4 abhydrolase domain containing 4
APLP2 amyloid beta (A4) precursor-like protein 2
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
CADM1 cell adhesion molecule 1
CALR calreticulin
CBR3 carbonyl reductase 3
CD163 CD163 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DLK1 delta-like 1 homolog (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP5 dual specificity phosphatase 5
EGR1 early growth response 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FASN fatty acid synthase
FN1 fibronectin 1
FUCA1 fucosidase, alpha-L- 1, tissue
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
HK2 hexokinase 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPB8 heat shock 22kDa protein 8
KIAA0226L KIAA0226-like
MAOA monoamine oxidase A
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEF2C myocyte enhancer factor 2C
NMB neuromedin B
NRCAM neuronal cell adhesion molecule
NRIP1 nuclear receptor interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PEG3 paternally expressed 3
PGD phosphogluconate dehydrogenase
PIR pirin (iron-binding nuclear protein)
PPAP2B phosphatidic acid phosphatase type 2B
PRUNE2 prune homolog 2 (Drosophila)
RGS1 regulator of G-protein signaling 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STC2 stanniocalcin 2
TSPAN7 tetraspanin 7
TXNRD1 thioredoxin reductase 1
UGCG UDP-glucose ceramide glucosyltransferase
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ALDOB aldolase B, fructose-bisphosphate
ANXA1 annexin A1
ASS1 argininosuccinate synthase 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTG3 BTG family, member 3
CAST calpastatin
CCNB2 cyclin B2
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CDK19 cyclin-dependent kinase 19
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLTB clathrin, light chain B
COL4A5 collagen, type IV, alpha 5
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DSG2 desmoglein 2
FAM114A1 family with sequence similarity 114, member A1
FPGS folylpolyglutamate synthase
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GOLT1B golgi transport 1B
H2BFS H2B histone family, member S (pseudogene)
HIST1H2AC histone cluster 1, H2ac
HOXA5 homeobox A5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFITM2 interferon induced transmembrane protein 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IGHM immunoglobulin heavy constant mu
ITGB1BP1 integrin beta 1 binding protein 1
KRT20 keratin 20, type I
KRT81 keratin 81, type II
LCN2 lipocalin 2
LGALS4 lectin, galactoside-binding, soluble, 4
MARCKS myristoylated alanine-rich protein kinase C substrate
MBNL2 muscleblind-like splicing regulator 2
MXRA5 matrix-remodelling associated 5
OPTN optineurin
PAM peptidylglycine alpha-amidating monooxygenase
PDGFD platelet derived growth factor D
PDLIM1 PDZ and LIM domain 1
PDZK1IP1 PDZK1 interacting protein 1
PEG10 paternally expressed 10
PF4 platelet factor 4
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PRSS2 protease, serine, 2 (trypsin 2)
PSCA prostate stem cell antigen
RCAN1 regulator of calcineurin 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEPP1 selenoprotein P, plasma, 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFRP1 secreted frizzled-related protein 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOSTDC1 sclerostin domain containing 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SPON2 spondin 2, extracellular matrix protein
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TM4SF1 transmembrane 4 L six family member 1
TMEM45A transmembrane protein 45A
TPM1 tropomyosin 1 (alpha)
TRIM22 tripartite motif containing 22
TRIM29 tripartite motif containing 29
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
WT1 Wilms tumor 1