BRD-K36737713_AG 957_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

86 genes differentially expressed following the BRD-K36737713_AG 957_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ATF3 activating transcription factor 3
BLVRB biliverdin reductase B
CA2 carbonic anhydrase II
CEMIP cell migration inducing protein, hyaluronan binding
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
COCH cochlin
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FN1 fibronectin 1
GCLM glutamate-cysteine ligase, modifier subunit
H2BFS H2B histone family, member S (pseudogene)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIRA histone cell cycle regulator
HIST1H2BK histone cluster 1, H2bk
HMOX1 heme oxygenase 1
HNMT histamine N-methyltransferase
HPCAL1 hippocalcin-like 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL17RB interleukin 17 receptor B
KIF14 kinesin family member 14
LITAF lipopolysaccharide-induced TNF factor
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MSRB1 methionine sulfoxide reductase B1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDLIM5 PDZ and LIM domain 5
PECR peroxisomal trans-2-enoyl-CoA reductase
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RHOB ras homolog family member B
S100P S100 calcium binding protein P
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC1 syndecan 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
AMIGO2 adhesion molecule with Ig-like domain 2
AREG amphiregulin
BHLHE41 basic helix-loop-helix family, member e41
CCND1 cyclin D1
CD24 CD24 molecule
DDIT4 DNA-damage-inducible transcript 4
DEPTOR DEP domain containing MTOR-interacting protein
DLK1 delta-like 1 homolog (Drosophila)
EREG epiregulin
GATA3 GATA binding protein 3
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOPX HOP homeobox
HOXB2 homeobox B2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
LPL lipoprotein lipase
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LTF lactotransferrin
LUM lumican
MBNL1 muscleblind-like splicing regulator 1
MYOF myoferlin
NPR3 natriuretic peptide receptor 3
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PFKP phosphofructokinase, platelet
PLCB4 phospholipase C, beta 4
PRAME preferentially expressed antigen in melanoma
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RCAN2 regulator of calcineurin 2
RGS1 regulator of G-protein signaling 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNS3 tensin 3
TOB1 transducer of ERBB2, 1
TPD52L1 tumor protein D52-like 1
TTC3 tetratricopeptide repeat domain 3
TXNIP thioredoxin interacting protein
ZBTB38 zinc finger and BTB domain containing 38
ZFPM2 zinc finger protein, FOG family member 2