BRD-K36007650_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K36007650_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP13 A kinase (PRKA) anchor protein 13
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASPN asporin
BAG3 BCL2-associated athanogene 3
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHIC2 cysteine-rich hydrophobic domain 2
COL10A1 collagen, type X, alpha 1
CSRP1 cysteine and glycine-rich protein 1
CUX1 cut-like homeobox 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
GARS glycyl-tRNA synthetase
GNAS GNAS complex locus
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IFRD1 interferon-related developmental regulator 1
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
MED13 mediator complex subunit 13
MT1M metallothionein 1M
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTUS1 microtubule associated tumor suppressor 1
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PCDH9 protocadherin 9
PDLIM5 PDZ and LIM domain 5
PPP1R15A protein phosphatase 1, regulatory subunit 15A
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TIMP3 TIMP metallopeptidase inhibitor 3

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADIRF adipogenesis regulatory factor
AHNAK2 AHNAK nucleoprotein 2
C6ORF62 chromosome 6 open reading frame 62
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CP ceruloplasmin (ferroxidase)
CTSV cathepsin V
DEPTOR DEP domain containing MTOR-interacting protein
DES desmin
GPM6A glycoprotein M6A
GPM6B glycoprotein M6B
HMGB3 high mobility group box 3
HP haptoglobin
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
LCN2 lipocalin 2
MAN1A1 mannosidase, alpha, class 1A, member 1
NLRP2 NLR family, pyrin domain containing 2
QPCT glutaminyl-peptide cyclotransferase
SST somatostatin
ZNF586 zinc finger protein 586