BRD-K35559145_Methotrimeprazine maleat salt_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

90 genes differentially expressed following the BRD-K35559145_Methotrimeprazine maleat salt_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTB actin, beta
ALAS2 5'-aminolevulinate synthase 2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
C10ORF10 chromosome 10 open reading frame 10
CA2 carbonic anhydrase II
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCNG2 cyclin G2
CCR2 chemokine (C-C motif) receptor 2
CDC42 cell division cycle 42
CNN3 calponin 3, acidic
DACH1 dachshund family transcription factor 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENO1 enolase 1, (alpha)
FAM129A family with sequence similarity 129, member A
FOXG1 forkhead box G1
GPER1 G protein-coupled estrogen receptor 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
ITGA6 integrin, alpha 6
LGALS3 lectin, galactoside-binding, soluble, 3
MME membrane metallo-endopeptidase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
RHOBTB1 Rho-related BTB domain containing 1
S100A12 S100 calcium binding protein A12
SATB2 SATB homeobox 2
SOX9 SRY (sex determining region Y)-box 9
SSBP2 single-stranded DNA binding protein 2
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ADGRG2 adhesion G protein-coupled receptor G2
AK2 adenylate kinase 2
AKR1C2 aldo-keto reductase family 1, member C2
ALCAM activated leukocyte cell adhesion molecule
AQP3 aquaporin 3 (Gill blood group)
ATF3 activating transcription factor 3
CCL19 chemokine (C-C motif) ligand 19
CCND1 cyclin D1
CD44 CD44 molecule (Indian blood group)
CD69 CD69 molecule
CDK6 cyclin-dependent kinase 6
COL10A1 collagen, type X, alpha 1
COMP cartilage oligomeric matrix protein
CP ceruloplasmin (ferroxidase)
CRABP1 cellular retinoic acid binding protein 1
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTSL cathepsin L
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEGS1 delta(4)-desaturase, sphingolipid 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM57A family with sequence similarity 57, member A
GAS1 growth arrest-specific 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IRS2 insulin receptor substrate 2
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
LAMB3 laminin, beta 3
MEIS1 Meis homeobox 1
MLEC malectin
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NAAA N-acylethanolamine acid amidase
NFIB nuclear factor I/B
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NUP62 nucleoporin 62kDa
OLFM1 olfactomedin 1
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
RRP1B ribosomal RNA processing 1B
SCG5 secretogranin V
SFN stratifin
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC38A1 solute carrier family 38, member 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SMAD2 SMAD family member 2
SORD sorbitol dehydrogenase
SYBU syntabulin (syntaxin-interacting)
THAP11 THAP domain containing 11
TMEM30B transmembrane protein 30B
TMEM45A transmembrane protein 45A
TOP2A topoisomerase (DNA) II alpha 170kDa
TPM1 tropomyosin 1 (alpha)
TPR translocated promoter region, nuclear basket protein
TRIM14 tripartite motif containing 14
TSPAN13 tetraspanin 13
TSPYL5 TSPY-like 5
TTC19 tetratricopeptide repeat domain 19
TYRP1 tyrosinase-related protein 1
WDR3 WD repeat domain 3
YBX3 Y box binding protein 3
ZMYM2 zinc finger, MYM-type 2